Associate Professor Chen-Han Huang
Posted on: 2021-06-08
Specialties：Nanostructure Biochemical Sensor、Functional Biochemical Materials、Biophotonics and Imaging System 、Deep Learning for Signal and Image Processing
Contact Information：03-4227151 (27753)
E-mail：chhuang@ncu.edu.tw
Education
08/2006 - 10/2009 Ph.D. Department of Photonics, National Cheng Kung University
Professional Experience
08/2017 – present Assistant professor in
Department of Biomedical Sciences and Engineering,
National Central University
10/2014 - 07/2017 Postdoctoral Research Fellow in
Department of Radiology,
Harvard Medical School, USA
10/2014 - 07/2017 Postdoctoral Research Fellow in
Center for Systems Biology,
Massachusetts General Hospital, USA
Honors
2020. 未來科技突破獎
2020. 國家新創獎-新創精進獎
2020. 台灣創新技術博覽會-銀牌
2020. 產學合作績優獎
2020. 校教學優良獎
2020. 新創千里馬創業競賽-優選
2020. 全球消費性電子展-新創獎 (Innovation Awards- CES)
2019. 未來科技突破獎-科技部
2019. 16th國家新創獎-新創精進獎
2019. 台灣創新技術博覽會-鉑金獎
2019. 新創之星-經濟日報
2018. 15th國家新創獎-學研新創獎
2018. 績優新創團隊-國立中央大學
2018. 創業潛力獎-FITI創新創業競賽
2018. 第一屆龍騰微笑智聯網創業競賽-冠軍
2018. 全球戰創客大賽-青年創新創業獎
2017. Outstanding New Faculty Award, National Central University
2016. Merit Poster Awards at MGH ORCD Research Fellows Poster Celebration
2016. Distinction Poster Awards at Annual Meeting of the MGH Scientific Advisory Committee
2014. The Postdoctoral Research Abroad Program (National Science Council of Taiwan)
2012. Postdoctoral Academic Research Merit Award (National Science Council of Taiwan)
2012. Young Researcher Innovation Research Award (Taiwan Comprehensive University System, T4)
Journal Paper
Peer-reviewed journal publication (SCI)
1. Chen-Han Huang#, Yong Il Park, Hsing-Ying Lin, Divya Pathania, Ki Soo Park, Maria Avila-Wallace, Cesar M. Castro, Ralph Weissleder, Hakho Lee, “Compact and Filter-Free Luminescence Biosensor for Mobile in Vitro Diagnoses,” ACS Nano, 2019, https://doi.org/10.1021/acsnano.9b05634. IF = 13.942. Rank: 3.27% (9/275,)
2. Abrina Roy, Hsing-Ying Lin, Chung-Yu Chou, Chen-Han Huang, Julia Small, Noah Sadik, Caroline M. Ayinon, Elizabeth Lansbury, Lilian Cruz, Anudeep Yekula, Pamela S. Jones, Leonora Balaj,OrcID and Bob S. Carter, “Navigating the Landscape of Tumor Extracellular Vesicle Heterogeneity,” Int. J. Mol. Sci. 2019, 20(6), 1349.
3. Jongmin Park, Hsing-Ying Lin, Jean Pierre Assker, Sangmoo Jeong, Chen-Han Huang, Ahmed Kurdi, Kyungheon Lee, Kyle Fraser, Changwook Min, Siawosh Eskandari , Sujit Routray, Bakhos Tannous, Reza Abdi, Leonardo Riella, Anil Chandraker, Cesar Castro, Ralph Weissleder, Hakho Lee, Jamil Azzi, “Integrated kidney exosome analysis (iKEA) for the detection of kidney transplant rejection,” ACS Nano, 2017, 11 (11), pp 11041–11046. IF = 13.942. Rank: 3.27% (9/275,).
4. Hsing-Ying Lin#, Chen-Han Huang#, Jongmin Park, Divya Pathania, Cesar M. Castro, Alessio Fasano, Ralph Weissleder, and Hakho Lee*, “Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection,” ACS Nano, 2017, 11 (10), pp 10062–10069. DOI: 10.1021/acsnano.7b04318. IF: 13.942, Rank: 3.27% (9/275,).
(co-first author)
5. Katherine S. Yang, Hyungsoon Im,, Seonki Hong, Ilaria Pergolini, Andres Fernandez del Castillo, Rui Wang, Susan Clardy, Chen-Han Huang, Craig Pille, Soldano Ferrone, Robert Yang, Cesar M. Castro, Hakho Lee, Carlos Fernandez del Castillo and Ralph Weissleder*, “Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy,” Science Translational Medicine, Vol. 9, p46527-46535 (2017/05). IF: 16.796, Rank: 1.56% (2/128).
(Science Publishing Group)
6. Yuan-Yu Chen, Yu-Cheng Fang, Shih-Yun Lin, Yi-Jyun Lin, Shih-Ying Yen, Chen-Han Huang, Chiou-Ying Yang, Lai-Kwan Chau*, Shau-Chun Wang*, “Corona-induced micro-centrifugal flows for concentration of Neisseria and Salmonella bacteria prior to their quantitation using antibody-functionalized SERS-reporter nanobeads,” Microchimica Acta, Vol. 184, p1021-1028 (2017/02). IF: 4.58, Rank: 10% (8/76).
7. Ki Soo Park#, Chen-Han Huang#, Kyungheon Lee, Yeong-Eun Yoo, Cesar M. Castro, Ralph Weissleder* and Hakho Lee*, “Rapid identification of health care–associated infections with an integrated fluorescence anisotropy system,” Science Advances, Vol. 2, no. 5 (2016/06). IF: 11.51
(Science Publishing Group).
(co-first author)
8. Yong Ii Park, Eunha Kim, Chen-Han Huang, Ki Soo Park, Hakho Lee* and Ralph Weissleder*, “Facile coating strategy to functionalize inorganic nanoparticles for biosensing”, Bioconjugate Chemistry, (2016/10). IF: 4.818, Rank: 12.9% (10/77).
9. Seonki Hong, David Pirovich, Aoife Kilcoyne, Chen-Han Huang, Hakho Lee, Ralph Weissleder*, “Supramolecular Metallo-Bioadhesive for Minimally Invasive Use,” Advanced Materials, Vol. 28, p 8675–8680 (2016/08) IF: 19.791, Rank: 1.3% (2/144).
10. Wen-Hao Chen, Yen-Ta Tseng, Shuchen Hsieh, Wan-Chun Liu, Chiung-Wen Hsieh, Chin-Wei Wu, Chen-Han Huang, Hsing-Ying Lin, Chao-Wen Chen, Pei-Ying Lin, and Lai-Kwan Chau*, “Silanization of solid surfaces via mercaptopropylsilatrane: a new approach of constructing gold colloid monolayers,” RSC Advances, Vol. 4, p46527-46535 (2014/09). IF: 3.84, Rank: 21% (33/157).
11. Hsing-Ying Lin#, Chen-Han Huang#, Wen-Hsin Hsieh, Ling-Hsuan Liu, Yuan-Chuen Lin, Chia-Chun Chu, Shi-Ting Wang, I-Ting Kuo, Lai-Kwan Chau*, and Chiou-Ying Yang, “On-line SERS Detection of Single Bacterium Using Novel SERS Nanoprobes and A Microfluidic Dielectrophoresis Device,” Small Vol. 10, p4700–4710 (2014/08). IF: 8.643, Rank: 6.1% (16/260). (Inside Front Cover)
(co-first author)
12. Chen-Han Huang, Hsing-Ying Lin, Cheng-Wen Huang, Yi-Min Liu, Fu-Yu Shih, Wei-Hua Wang and Hsiang-Chen Chui*, “Probing substrate influence on graphene by analyzing Raman lineshapes,” Nanoscale Research Letters, Vol. 9:64 (2014/07). IF: 2.833, Rank: 18% (26/144).
13. Hsing-Ying Lin, Meei-Ling Hung, Chen-Han Huang*, Hsiang-Chen Chui, Jui-Sheng Lin, “Graphene layer number dependent size distribution of silver nanoparticles,” Applied Physics A, Vol. 115, p399-402 (2014/05). IF: 1.7, Rank: 45% (65/144).
(corresponding author)
14. Hsing-Ying Lin#, Chen-Han Huang#, Hin-Hong Lu, I-Ting Kuo, and Lai-Kwan Chau*, “Direct Detection of Orchid Viruses Using Nanorod-Based Fiber Optic Particle Plasmon Resonance Immunosensor,” Biosensors and Bioelectronics, Vol. 51, p371–378 (2014/01),
IF: 7.78, Rank: 3.5% (1/28). (Key Scientific Article, Global Medical Discovery.)
(co-first author)
15. Hsing-Ying Lin#, Chen-Han Huang#, Yu-Chia Liu, Shin-Huei Chen, and Lai-Kwan Chau, “Tubular Waveguide Evanescent Field Absorption Biosensor Based on Particle Plasmon Resonance for Multiplex Label-free Detection,” Biosensors and Bioelectronics, Vol. 41, p268–274 (2013/03).
IF: 6.451, Rank: 3.7% (1/27).
(co-first author)
16. Cheng-En Cheng, Chi-Yuan Lin, Hao-Yu Chang, Chen-Han Huang, Hsing-Ying Lin, Chia-Hao Chen, Chia-Chen Hsu, Chen-Shiung Chang,and Forest Shih-Sen Chien* “Surface-enhanced Raman scattering of graphene with photo-assisted-synthesized gold nanoparticles,” Optics Express, Vol. 21, Issue 5, p6547-6554 (2013/03). IF: 3.525, Rank: 7.2% (6/83).
17. Cheng-Wen Huang, Bing-Jie Lin, Hsing-Ying Lin, Chen-Han Huang, Fu-Yu Shih, Wei-Hua Wang, Chih-Yi Liu and Hsiang-Chen Chui*, “Surface-enhanced Raman scattering of suspended monolayer graphene,” Nanoscale Research Letters, 8:480 (2013/11). IF: 2.833, Rank: 18% (44/241).
18. Chen-Han Huang, Hsing-Ying Lin, Yonhua Tzeng, Chien-Hsiang Fan, Chih-Yi Liu, Chia-Yi Li, Cheng-Wen Huang, and Hsiang-Chen Chui*, “Optical characteristics of pore size on porous anodic aluminium oxide films with embedded silver nanoparticles,” Sensors & Actuators: A, Vol. 180, p49-54 (2012/06). IF: 2.201, Rank: 17% (10/56).
19. Chen-Han Huang, Hsing-Ying Lin, Yonhua Tzeng, Chien-Hsiang Fan, Chih-Yi Liu, Chia-Yi Li, Cheng-Wen Huang, and Hsiang-Chen Chui*, “Tunable Photoconductivity of Porous Anodic Aluminum Oxide with Silver Nanoparticles,” Electrochemical and Solid State Letters, Vol. 15, pJ14-J17 (2012/01). IF: 2.321, Rank: 25% (65/260).
20. Hsing-Ying Lin#, Chen-Han Huang#, Lai-Kwan Chau*, “Fiber Optic Particle Plasmon Resonance Sensor Based on Plasmonic Light Scattering Interrogation,” Annalen der Physik, Vol. 524(11), p705–712 (2012/11). IF: 3.443, Rank: 14% (11/79). (Invited Paper for Special Issue: Plasmonic Sensors.)
(co-first author)
21. Hsing-Ying Lin#, Chen-Han Huang#, Shannon Shy, Yu-Chung Chang*, Hsiang-Chen Chui*, and Chih-Han Chang, “Visibility Enhancement of Common Bile Duct for Laparoscopic Cholecystectomy by Vivid Fiber-optic Indication: A Porcine Experiment Trial,” Biomedical Optics Express, Vol. 3, p1964-1971 (2012/09). IF: 3.176, Rank: 8.7% (7/80).
22. Hsing-Ying Lin, Chen-Han Huang*, Gia-Ling Cheng, Nan-Kuang Chen, and Hsiang-Chen Chui, “Tapered optical fiber sensor based on localized surface plasmon resonance,” Optics Express, Vol. 20, p21693-21701 (2012/09). IF: 3.546, Rank: 6.2% (5/80), Cited: 49. (Selected in Virtual Journal for Biomedical Optics)
(corresponding author)
23. Hsing-Ying Lin, Chen-Han Huang*, Chia-Chi Huang, Yu-Chia Liu, and Lai-Kwan Chau*, “Multiple resonance fiber-optic sensor with time division multiplexing for multi-analyte detection,” Optics Letters, Vol. 37, p3969-3971 (2012/10). IF: 3.385, Rank: 7.5% (6/80).
(corresponding author)
24. Chia-Chi Huang, Chen-Han Huang, I-Ting Kuo, Lai-Kwan Chau*, Tzzy-Schiuan Yang*, “Synthesis of silica-coated gold nanorod as Raman tags by modulating cetyltrimethylammonium bromide concentration,” Colloid Surf. A-Physicochem. Eng. Asp., Vol. 409, p 161-166 (2012/09). IF: 2.76, Rank: 35% (50/139).
25. Cheng-Wen Huang, Hsing-Ying Lin, Chen-Han Huang, Kai-Hong Lo, Yu-Chung Chang,Chih-Yi Liu, Chen-Hao Wu, Yonhua Tzeng, and Hsiang-Chen Chui*, “Fluorescence Quenching due to Sliver Nanoparticles Covered by Graphene and Hydrogen-Terminated Graphene,” Appl. Phys. Lett., Vol 102, p053113 (2013/02). IF: 3.515, Rank: 14% (20/136).
26. Cheng-Wen Huang, Hsing-Ying Lin, Chen-Han Huang, Ren-Jye Shiue, Wei-Hua Wang, Chih-Yi Liu and Hsiang-Chen Chui*, “Layer-Dependent Morphologies of Silver on N-Layer Graphene,” Nanoscale Research Letters, 7:618 (2012/09). IF: 2.833, Rank: 18% (44/241).
27. S.-T. Chen, Y.-C. Chu, C.-Y. Liu, Chen-Han Huang, Y. Tzeng*, “Surface-enhanced Raman spectroscopy for characterization of nanodiamond seeded substrates and ultrananocrystalline diamond at the early-stage of plasma CVD growth process,” Diamond and Related Materials, Vol. 24, p161-166 (2012/04). IF: 2.561, Rank: 35% (97/275).
28. Cheng-Wen Huang, Bing-Jie Lin, Hsing-Ying Lin, Chen-Han Huang, Fu-Yu Shih, Wei-Hua Wang, Chih-Yi Liu and Hsiang-Chen Chui*, “Observation of Strain Effect on the Suspended Graphene by Polarized Raman Spectroscopy,” Nanoscale Research Letters, Vol. 7:533 (2012/09). IF: 2.78, Rank: 18% (44/241), Cited: 8.
29. Chen-Han Huang, Hsing-Ying Lin, Shihtse Chen, Chih-Yi Liu, Hsiang-Chen Chui, and Yonhua Tzeng*, “Electrochemically fabricated self-aligned 2-D silver/alumina arrays as reliable SERS sensors,” Optics Express, Vol. 19, p11441-11450 (2011/06). IF: 3.587, Rank: 7.5% (6/79).
30. K. R. Chen*, W. H. Chu, H. C. Fang, C. P. Liu, Chen-Han Huang, H. C. Chui, C. H. Chuang, Y. L. Lo, C. Y. Lin, H. H. Hwung, and Andy Y.-G. Fuh, “Beyond-limit light focusing in the intermediate zone,” Optics Letter, Vol. 36, p4497-4499 (2011/11). IF: 3.399, Rank: 8.8% (7/79)
31. Yi-Chi Lee, Chin-Chun Tsai, Yung-Yung Chang, Chen-Han Huang, and Hsiang-Chen Chui*, “Determining hyperfine transitions with electromagnetically induced transparency and optical pumping,” Chinese Physics B, Vol. 20, p073101 (2011/07). IF: 1.376.
32. Ben-Chao Lau, Chih-Yi Liu, Hsing-Ying Lin, Chen-Han Huang, Hsiang-Chen Chui, and Yonhua Tzeng*, “Electrochemical fabrication of anodic aluminum oxide films with encapsulated silver nanoparticles as plasmonic photoconductors,” Electrochemical and Solid-State Letters, Volume 14, E15-E17 (2011/02). IF: 2.321, Rank: 25% (65/260).
33. Hsing-Ying Lin, Chen-Han Huang, Chih-Han Chang, Yung-Chiang Lan, and Hsiang-Chen Chui*, “Direct near-field optical imaging of plasmonic resonances in metal nanoparticle pairs,” Optics Express, Vol. 18, p165-172 (2010). (Selected in Virtual Journal for Biomedical Optics)IF: 3.753, Rank: 6.4% (6/79).
34. Zong-Yan Zhuo, Chien-Sheng Liao, Chen-Han Huang, Jiun-Yann Yu, Yu-Yi Tzeng, Wen Lo, Chen-Yuan Dong, Hsiang-Chen Chui, Yu-Chan Huang, Hsi-Mei Lai, Shi-Wei Chu*, “Second harmonic generation imaging – A new method for unraveling molecular information of starch,” Journal of Structural Biology, Vol. 171, p88-94 (2010/07). IF: 3.50.
35. Chen-Han Huang, Hsing-Ying Lin, Ben-Chao Lau, Chih-Yi Liu, Hsiang-Chen Chui, Yonhua Tzeng*, “Plasmon-induced optical switching of electrical conductivity in porous anodic aluminum oxide films encapsulated with silver nanoparticle arrays,” Optics Express, Vol. 18, p27891-27899 (2010/11).
IF: 3.753, Rank: 6.4% (6/79).
36. Yan-Wei Tzeng, Yen-Yin Lin, Chen-Han Huang, Jian-Ming Liu, Hsiang-Chen Chui, Hsiang-Lin Liu, James M. Stone, Jonathan C. Knight, and Shi-Wei Chu*, “Broadband tunable optical parametric amplification from a single 50 MHz ultrafast fiber laser,” Optics Express, Vol. 17, Issue 9, p7304-7309 (2009/04).
IF: 3.278, Rank: 4.2% (3/71).
37. Jiun-Yann Yu, Chien-Sheng Liao, Zong-Yan Zhuo, Chen-Han Huang, Hsiang-Chen Chui, and Shi-Wei Chu*, “A diffraction-limited scanning system providing broad spectral range for laser scanning microscopy,” Review of Scientific Instruments, Vol. 80, p113704 (2009/11). IF: 1.521.
38. Chen-Han Huang, Hsing-Ying Lin, Hsiang-Chen Chui*, Yung-Chiang Lan, and Shi-Wei Chu, “The phase-response effect of size-dependent optical enhancement in a single nanoparticle,” Optics Express, Vol. 16, p9580-9586 (2008/06). IF: 3.88, Rank: 4.6% (5/78).
Book
39. Hsing-Ying Lin, Md. Nurunnabi, Wen-Hao Chen, Chen-Han Huang*, “Graphene in photoelectrochemical sensor and biosensor,” Chapter 16 of Book: Biomedical Applications of Graphene and 2D Nanomaterials; Publisher: ELSEVIER. Ltd. (2019)
40. Hsing-Ying Lin, Md. Nurunnabi, Wen-Hao Chen, Chen-Han Huang*, “Application of 2D nanomaterials in biomedical device,” Chapter 17 of Book: Biomedical Applications of Graphene and 2D Nanomaterials; Publisher: ELSEVIER. Ltd. (2019)
41. Hsing-Ying Lin, Ping-Ji Huang, Chen-Han Huang, Yen-Chieh Wang, Churng-Ren Chris Wang*, “Synthesis and optical properties of noble metal nanoparticles for biodetection,” Chapter 1 of Book: From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection; Publisher: Pan Stanford Publishing Pte. Ltd.; Editors: Lai-Kwan Chau, Huan-Tsung Chang; Publication Date: September 30, 2012 | ISBN-10: 9814267244 | ISBN-13: 978-9814267243 | Edition: 1.
Domestic publication
42. Hsing-Ying Lin, Chen-Han Huang, Lai-Kwan Chau,” Novel Optical Nanoprobes: SERS Tags for Biochemical Sensing and Applications,” CHEMISTRY (The Chinese Chemical Society, Taipei), Vol. 71, No. 3, pp. 243-2521 (2013).
43. Chen-Han Huang, Hsing-Ying Lin, Lai-Kwan Chau, “Novel Optical Nanoprobes: Raman-labeled Nanoaggregate-embedded Beads,” Taipei international invention show & technomart (2013/09), Taiwan nano exhibition (2013/10), Taiwan medical and biotech industry association (2013/12).
NCKU R&D News
44. Hsing-Ying Lin, Chen-Han Huang, Yun-Chiang Lan, Chih-Han Chang, and Hsiang-Chen Chui*, ”Plasmonic resonances of gold nanoparticle pairs,” Research Express@NCKU, Volume 24 Issue 1 (2013/05).
45. Chen-Han Huang, Hsing-Ying Lin, Hsiang-Chen Chui*, Yun-Chiang Lan, Chih-Han Chang, and Shi-Wei Chu, ”The phase-response effect of size-dependent optical enhancement in a single nanoparticle,” Research Express@NCKU, Volume 11 Issue 5 (2009/11).
EI and conference papers
1. Chen-Han Huang, Hsing-Ying Lin, Chien-Hsiang Fan, and Hsiang-Chen Chui*, “Near-infrared supercontinuum generation in conventional single mode fiber used for optical sensors,” 11th IEEE International Conference on Control & Automation (ICCA 2014), Taichung, Taiwan, (2014/06).
2. Chen-Han Huang*, Hsing-Ying Lin, Ling-Hsuan Liu, Shi-Ting Wang, I-Ting Kuo, Wen-Hsin Hsieh, Chiou-Ying Yang, and Lai-Kwan Chau*, “Bacteria detection using surface-enhanced Raman spectroscopic nanoprobes and dielectrophoretic microfluidic chip,” Biosensors 2014, 24th Anniversary World Congress on Biosensors, Melbourne, Australia, (2014/05).
3. Chen-Han Huang*, Hsing-Ying Lin, Ling-Hsuan Liu, Shi-Ting Wang, I-Ting Kuo, Wen-Hsin Hsieh, Chiou-Ying Yang, and Lai-Kwan Chau, “Bacteria detection using Raman-labeled nanoaggregate-embedded beads and dielectrophoretic chip,” EUROPT(R)ODE XII Conference on Optical Chemical Sensors & Biosensors, Athens, Greece, (2014/04).
4. Hsing-Ying Lin*, Chen-Han Huang, Lai-Kwan Chau, “Multiwindow fiber-optic plasmonic sensing based on light scattering,”EUROPT(R) ODE XII Conference on Optical Chemical Sensors & Biosensors, Athens, Greece,(2014/04).
5. Chen-Han Huang*, Hsing-Ying Lin, Wen-Hsin Hsieh, and Lai-Kwan Chau, “SERS Analysis for Pathogen Detection Using Raman-labeled Nanoaggregate-embedded Beads with A Dielectrophoretic Chip,” The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials (ASAM-4) , (2013/10).
6. Chen-Han Huang*, Hsing-Ying Lin, Wen-Hsin Hsieh, and Lai-Kwan Chau, “SERS Analysis for Pathogen Detection Using Raman-labeled Nanoaggregate-embedded Beads with A Dielectrophoretic Chip,” The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials (ASAM-4) , (2013/10).
7. Chen-Han Huang, Hsing-Ying Lin*, and Lai-Kwan Chau, “Tubular optical waveguide particle plasmon resonance biosensor for multiplex real-time and label-free detection,” Optical Sensors 2013, SPIE Optics + Optoelectronics, Prague, Czech Republic, (2013/04) (EI)
8. Chen-Han Huang*, Hsing-Ying Lin, and Lai-Kwan Chau, “Plasmonic Scattering Fiber Optic Sensor for Higher-Throughput Multianalyte Detection,” 3rd International Conference on Bio-Sensing Technology, Sitges, Spain, (2013/05).
9. Hsing-Ying Lin, Chen-Han Huang*, and Lai-Kwan Chau, “Multianalyte detection using fiber optic particle plasmon resonance sensor based on plasmonic light scattering interrogation,” Optical Sensors 2013, SPIE Optics + Optoelectronics, Prague, Czech Republic, (2013/04) (EI)
10. Hsing-Ying Lin, Chen-Han Huang*, Hsiang-Chen Chui, Meei-Ling Hung, “Silver nanoparticle distribution with the dependence of graphene layer number,” META’13, the 4th International Conference on Metamaterials, Photonic Crystals and Plasmonics, University of Sharjah, Sharjah, UAE, (2013/03) (submitted to Special issue of the journal Applied Physics A (Springer)) (EI)
11. Hsing-Ying Lin, Chen-Han Huang*, and Lai-Kwan Chau*, “Multiple Resonance Fiber-Optic Sensor with Multiplexing Technique for Simultaneous Multianalyte Detection,” 19th-Conference of Chemical Analysis Techniques (2103). (Invited Speaker)
12. Hsing-Ying Lin*, Chen-Han Huang, and Lai-Kwan Chau, “Dual Resonance Fiber-Optic Sensor with Frequency-Division
Multiplexing for Simultaneous Detection of Two Analytes,” 3rd International Conference on Bio-Sensing Technology, Sitges, (2013/05).
13. Hsing-Ying Lin*, Chen-Han Huang, Sin-Hong Lu, I-Ting Kuo, and Lai-Kwan Chau*, “Direct Detection of Orchid Viruses Using Gold Nanorod-Based Fiber Optic Particle Plasmon Resonance Immunosensor,” The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials (ASAM-4), (2013/10).
14. Hsing-Ying Lin, Chen-Han Huang, Hin-Hong Lu, I-Ting Kuo, and Lai-Kwan Chau*, “Detection of Orchid Viruses Using Nanorod-Based Fiber Optic Particle Plasmon Resonance Immunosensor,” 3rd International Conference on Bio-Sensing Technology, Sitges, Spain, (2013/05).
15. Meei-Ling Hung, Jeng-Wei Yang, Chen-Han Huang, Hsing-Ying Lin*, “Photoreduction mechanism of the sliver nanoparticles for active surface-enhanced Raman substrate by femtosecond laser,” The 7th Intelligent Systems Conference on Engineering Applications, (213/05) (EI).
16. Shi-Ting Wang, Hsing-Ying Lin, Chen-Han Huang, I-Ting Kuo, Lai-Kwan Chau*, “Development of Dielectrophoresis Chip Based on Gold Microelectrodes for Integration with Raman-Labeled Nanoaggregate-Embedded Beads in Pathogen Detection”, 19th-Conference of Chemical Analysis Techniques (2103).
17. Cheng-wen Huang, Bing-Jie Lin, Hsing-Ying Lin, Chen-Han Huang, Fu-Yu Shih, Wei-Hua Wang, Chih-Yi Liu, and Hsiang-Chen Chui*, “Probing Substrate Influence on Graphene by Raman Spectroscopy,” Annual Meeting of the Physics Society, Republic of China, Taiwan, (2103).
18. Chen-Han Huang, Hsing-Ying Lin, I-Ting Kuo, Wen-Hsin Hsieh, Ping-Ji Huang, Tzyy-Schiuan Yang, and Lai-Kwan Chau, “On-chip SERS analysis for single mimic pathogen detection using Raman-labeled nanoaggregate-embedded beads with a dielectrophoretic chip,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01). (EI)
19. Chen-Han Huang and Hsing-Ying Lin, “Fabrication of 2D metal nanoparticle array encapsulated by anodic aluminum oxide and its applications to surface-enhanced Raman scattering,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01) (EI)
20. Hsing-Ying Lin, Chen-Han Huang, Cheng-Wen Huang, Chia-Ling Cheng, Nan-Kuang Chen, Hsiang-Chen Chui*, “The localized surface plasmon resonance sensor based on tapered optical fiber modified with gold nanoparticles,” 2012 Asia Communications and Photonics Conference (ACP 2012), Guangzhou, China, (2012/11) (EI)
21. Hsing-Ying Lin, Chen-Han Huang, Yu-Chia Liu, Shin-Huei Chen, and Lai-Kwan Chau, “Tubular optical waveguide-based particle plasmon resonance biosensor for label-free and real-time detection,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01) (EI)
22. Hsing-Ying Lin, Chen-Han Huang, Yu-Chia Liu, Kuo-Wei Huang, and Lai-Kwan Chau, “Multiplex fiber-optic biosensor using multiple particle plasmon resonances,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01). (EI)
23. Hsing-Ying Lin, Chen-Han Huang, Chia-Ling Cheng, Nan-Kuang Chen, and Hsiang-Chen Chui, “Tapered fiber-optic LSPR sensor with metal nanoparticle layers,” PIERS 2012, Moscow, Russia, (2012/08) (EI)
Patent
US patent
1. L.-K. Chau, C.-H. Huang, H.-Y. Lin, Y.-C. Liu, “Multiplex fiber optical biosensor and detection method by using the same,” US patent, No. US 9464986 B2, 2016/10/11
2. H.-C. Chui, S. S.-Y. Juang, H.-Y. Lin, C.-H. Huang, H.-H. Liao, “Ultraviolet laser sterilization system,” US patent, No. US9061083 B2, 2015/06/23
3. Y.-H. Tzeng, C.-Y. Liu, C.-H.-Huang, H.-Y. Lin, H.-C. Chui, K.-O. Lau, S.-T. Chen, C.-W. Huang, “Sensor chip for biomedical and micro-nano structured objects and materials and method providing the same,” US patent, No. US8902420, 2014/12/02
4. Yon-Hua Tzeng, Chih-Yi Liu, Kyaw-Oo Lau, Hsiang-Chen Chui, Chen-Han Huang, Hsing-Ying Lin, “Photo-sensitive composite film, method of fabricating the same, and photo-switched device comprising the same,” US patent, No. US008461511B2, 2013/06/11
5. Yen-Yin Lin, Yan-Wei Tzeng, Chen-Han Huang, Jian-Ming Liu, Shi-Wei Chu, “Wavelength Tunable Single-Pass Optical Parametric Amplifier,” US patent, No. US8369003B2, 2013/02/05
UK patent
6. CHAU, LAI KWAN, CHIANG, CHANG YUE, CHIANG, CHUNG SHENG, HSIEH, WEN HSIN, HUANG, CHEN HAN, “Optical waveguide type particle plasma resonance sensing system,” UK patent, No. GB2517955, 2016/06/08
Taiwan (ROC) patent
7. CHAU, LAI-KWAN, LIN, HSING-YING, HUANG, CHEN-HAN, LIU, LING-HSUAN, HSIEH, WEN-HSIN, “ MICROFLUIDIC BIOSENSING SYSTEM”, ROC Patent, No. I506265, 2015/11/01
8. CHAU, LAI KWAN, CHIANG, CHANG YUE, CHIANG, CHUNG SHENG, HSIEH, WEN HSIN, HUANG, CHEN HAN, “ OPTICAL WAVEGUIDE-PARTICLE PLASMON RESONANCE SENSING SYSTEM”, ROC Patent, No. I484155, 2015/05/11
9. CHAU, LAI KWAN, HUANG, CHEN HAN, LIN, HSING YING, LIU, YU CHIA, “ MULTIPLEX FIBER OPTICAL BIOSENSOR AND DETECTION METHOD BY USING THE SAME”, ROC Patent, No. I472746, 2015/02/11
10. TZENG, YON HUA, LIU, CHIH YI, KYAW, KYAW-OO, CHUI, HSIANG CHEN, HUANG, CHEN HAN, LIN, HSING YING, “ PHOTO-SWITCHED PATTERNED STRUCTURE AND METHOD OF FABRICATING THE SAME”, ROC Patent, No. I465611, 2014/12/21
11. TZENG, YON HUA, LIU, CHIH YI, HUANG, CHEN HAN, LIN, HSING YING, CHUI, HSIANG CHEN, LAU, KYAW-OO, CHEN, SHIH TSE, HUANG, CHENG WEN, “ SENSOR CHIP FOR BIOMEDICAL AND MICRO-NANO STRUCTURED OBJECTS AND MATERIALS AND METHOD PROVIDING THE SAME”, ROC Patent, No. I456195, 2014/10/11
12. LIN, YEN YIN, TZENG, YAN WEI, HUANG, CHEN HAN, LIU, JIAN MING, CHU, SHI WEI, “ WAVELENGTH TUNABLE SINGLE PASS OPTICAL PARAMETRIC AMPLIFIER”, ROC Patent, No. I408481, 2013/09/11
13. TZENG, YON HUA, LIU, CHIH YI, KYAW, KYAW-OO, CHUI, HSIANG CHEN, HUANG, CHEN HAN, LIN, HSING YING, “ PHOTO-SWITCHED ANODIZED ALUMINUM OXIDE FILM, METHOD OF FABRICATING THE SAME, AND PHOTO-SWITCHED DEVICE COMPRISING THE SAME”, ROC Patent, No. I406302, 2013/08/21
14. CHUI, HSIANG CHEN, JUANG, SEAN SUNG YEN, LIN, HSING YING, HUANG, CHEN HAN, LIAO, HUA HSIEN, “ ULTRAVIOLET LASER STERILIZATION SYSTEM’’, ROC Patent, No. 102129288, 2015/02/16
China patent
15. H.-C. Chui, S. S.-Y. Juang, H.-Y. Lin, C.-H. Huang, H.-H. Liao, “ Ultraviolet laser sterilization system,” China patent, No. CN 104368020 A, 2015/02/25
16. Y.-H. Tzeng, C.-Y. Liu, C.-H.-Huang, H.-Y. Lin, H.-C. Chui, K.-O. Lau, S.-T. Chen, C.-W. Huang, “ Sensor chip for biomedical and micro-nano structured objects and materials and method providing the same,” China patent, No. CN 102621122 A, CN 102621122 B, 2014/07/09
17. CHAU, LAI KWAN, CHIANG, CHANG YUE, CHIANG, CHUNG SHENG, HSIEH, WEN HSIN, HUANG, CHEN HAN, “ Optical waveguide type particle plasma resonance sensing system,” China patent, No. CN 104422669 A, 2015/03/18
Contact Information：03-4227151 (27753)
E-mail：chhuang@ncu.edu.tw
Education
08/2006 - 10/2009 Ph.D. Department of Photonics, National Cheng Kung University
Professional Experience
08/2017 – present Assistant professor in
Department of Biomedical Sciences and Engineering,
National Central University
10/2014 - 07/2017 Postdoctoral Research Fellow in
Department of Radiology,
Harvard Medical School, USA
10/2014 - 07/2017 Postdoctoral Research Fellow in
Center for Systems Biology,
Massachusetts General Hospital, USA
Honors
2020. 未來科技突破獎
2020. 國家新創獎-新創精進獎
2020. 台灣創新技術博覽會-銀牌
2020. 產學合作績優獎
2020. 校教學優良獎
2020. 新創千里馬創業競賽-優選
2020. 全球消費性電子展-新創獎 (Innovation Awards- CES)
2019. 未來科技突破獎-科技部
2019. 16th國家新創獎-新創精進獎
2019. 台灣創新技術博覽會-鉑金獎
2019. 新創之星-經濟日報
2018. 15th國家新創獎-學研新創獎
2018. 績優新創團隊-國立中央大學
2018. 創業潛力獎-FITI創新創業競賽
2018. 第一屆龍騰微笑智聯網創業競賽-冠軍
2018. 全球戰創客大賽-青年創新創業獎
2017. Outstanding New Faculty Award, National Central University
2016. Merit Poster Awards at MGH ORCD Research Fellows Poster Celebration
2016. Distinction Poster Awards at Annual Meeting of the MGH Scientific Advisory Committee
2014. The Postdoctoral Research Abroad Program (National Science Council of Taiwan)
2012. Postdoctoral Academic Research Merit Award (National Science Council of Taiwan)
2012. Young Researcher Innovation Research Award (Taiwan Comprehensive University System, T4)
Journal Paper
Peer-reviewed journal publication (SCI)
1. Chen-Han Huang#, Yong Il Park, Hsing-Ying Lin, Divya Pathania, Ki Soo Park, Maria Avila-Wallace, Cesar M. Castro, Ralph Weissleder, Hakho Lee, “Compact and Filter-Free Luminescence Biosensor for Mobile in Vitro Diagnoses,” ACS Nano, 2019, https://doi.org/10.1021/acsnano.9b05634. IF = 13.942. Rank: 3.27% (9/275,)
2. Abrina Roy, Hsing-Ying Lin, Chung-Yu Chou, Chen-Han Huang, Julia Small, Noah Sadik, Caroline M. Ayinon, Elizabeth Lansbury, Lilian Cruz, Anudeep Yekula, Pamela S. Jones, Leonora Balaj,OrcID and Bob S. Carter, “Navigating the Landscape of Tumor Extracellular Vesicle Heterogeneity,” Int. J. Mol. Sci. 2019, 20(6), 1349.
3. Jongmin Park, Hsing-Ying Lin, Jean Pierre Assker, Sangmoo Jeong, Chen-Han Huang, Ahmed Kurdi, Kyungheon Lee, Kyle Fraser, Changwook Min, Siawosh Eskandari , Sujit Routray, Bakhos Tannous, Reza Abdi, Leonardo Riella, Anil Chandraker, Cesar Castro, Ralph Weissleder, Hakho Lee, Jamil Azzi, “Integrated kidney exosome analysis (iKEA) for the detection of kidney transplant rejection,” ACS Nano, 2017, 11 (11), pp 11041–11046. IF = 13.942. Rank: 3.27% (9/275,).
4. Hsing-Ying Lin#, Chen-Han Huang#, Jongmin Park, Divya Pathania, Cesar M. Castro, Alessio Fasano, Ralph Weissleder, and Hakho Lee*, “Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection,” ACS Nano, 2017, 11 (10), pp 10062–10069. DOI: 10.1021/acsnano.7b04318. IF: 13.942, Rank: 3.27% (9/275,).
(co-first author)
5. Katherine S. Yang, Hyungsoon Im,, Seonki Hong, Ilaria Pergolini, Andres Fernandez del Castillo, Rui Wang, Susan Clardy, Chen-Han Huang, Craig Pille, Soldano Ferrone, Robert Yang, Cesar M. Castro, Hakho Lee, Carlos Fernandez del Castillo and Ralph Weissleder*, “Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy,” Science Translational Medicine, Vol. 9, p46527-46535 (2017/05). IF: 16.796, Rank: 1.56% (2/128).
(Science Publishing Group)
6. Yuan-Yu Chen, Yu-Cheng Fang, Shih-Yun Lin, Yi-Jyun Lin, Shih-Ying Yen, Chen-Han Huang, Chiou-Ying Yang, Lai-Kwan Chau*, Shau-Chun Wang*, “Corona-induced micro-centrifugal flows for concentration of Neisseria and Salmonella bacteria prior to their quantitation using antibody-functionalized SERS-reporter nanobeads,” Microchimica Acta, Vol. 184, p1021-1028 (2017/02). IF: 4.58, Rank: 10% (8/76).
7. Ki Soo Park#, Chen-Han Huang#, Kyungheon Lee, Yeong-Eun Yoo, Cesar M. Castro, Ralph Weissleder* and Hakho Lee*, “Rapid identification of health care–associated infections with an integrated fluorescence anisotropy system,” Science Advances, Vol. 2, no. 5 (2016/06). IF: 11.51
(Science Publishing Group).
(co-first author)
8. Yong Ii Park, Eunha Kim, Chen-Han Huang, Ki Soo Park, Hakho Lee* and Ralph Weissleder*, “Facile coating strategy to functionalize inorganic nanoparticles for biosensing”, Bioconjugate Chemistry, (2016/10). IF: 4.818, Rank: 12.9% (10/77).
9. Seonki Hong, David Pirovich, Aoife Kilcoyne, Chen-Han Huang, Hakho Lee, Ralph Weissleder*, “Supramolecular Metallo-Bioadhesive for Minimally Invasive Use,” Advanced Materials, Vol. 28, p 8675–8680 (2016/08) IF: 19.791, Rank: 1.3% (2/144).
10. Wen-Hao Chen, Yen-Ta Tseng, Shuchen Hsieh, Wan-Chun Liu, Chiung-Wen Hsieh, Chin-Wei Wu, Chen-Han Huang, Hsing-Ying Lin, Chao-Wen Chen, Pei-Ying Lin, and Lai-Kwan Chau*, “Silanization of solid surfaces via mercaptopropylsilatrane: a new approach of constructing gold colloid monolayers,” RSC Advances, Vol. 4, p46527-46535 (2014/09). IF: 3.84, Rank: 21% (33/157).
11. Hsing-Ying Lin#, Chen-Han Huang#, Wen-Hsin Hsieh, Ling-Hsuan Liu, Yuan-Chuen Lin, Chia-Chun Chu, Shi-Ting Wang, I-Ting Kuo, Lai-Kwan Chau*, and Chiou-Ying Yang, “On-line SERS Detection of Single Bacterium Using Novel SERS Nanoprobes and A Microfluidic Dielectrophoresis Device,” Small Vol. 10, p4700–4710 (2014/08). IF: 8.643, Rank: 6.1% (16/260). (Inside Front Cover)
(co-first author)
12. Chen-Han Huang, Hsing-Ying Lin, Cheng-Wen Huang, Yi-Min Liu, Fu-Yu Shih, Wei-Hua Wang and Hsiang-Chen Chui*, “Probing substrate influence on graphene by analyzing Raman lineshapes,” Nanoscale Research Letters, Vol. 9:64 (2014/07). IF: 2.833, Rank: 18% (26/144).
13. Hsing-Ying Lin, Meei-Ling Hung, Chen-Han Huang*, Hsiang-Chen Chui, Jui-Sheng Lin, “Graphene layer number dependent size distribution of silver nanoparticles,” Applied Physics A, Vol. 115, p399-402 (2014/05). IF: 1.7, Rank: 45% (65/144).
(corresponding author)
14. Hsing-Ying Lin#, Chen-Han Huang#, Hin-Hong Lu, I-Ting Kuo, and Lai-Kwan Chau*, “Direct Detection of Orchid Viruses Using Nanorod-Based Fiber Optic Particle Plasmon Resonance Immunosensor,” Biosensors and Bioelectronics, Vol. 51, p371–378 (2014/01),
IF: 7.78, Rank: 3.5% (1/28). (Key Scientific Article, Global Medical Discovery.)
(co-first author)
15. Hsing-Ying Lin#, Chen-Han Huang#, Yu-Chia Liu, Shin-Huei Chen, and Lai-Kwan Chau, “Tubular Waveguide Evanescent Field Absorption Biosensor Based on Particle Plasmon Resonance for Multiplex Label-free Detection,” Biosensors and Bioelectronics, Vol. 41, p268–274 (2013/03).
IF: 6.451, Rank: 3.7% (1/27).
(co-first author)
16. Cheng-En Cheng, Chi-Yuan Lin, Hao-Yu Chang, Chen-Han Huang, Hsing-Ying Lin, Chia-Hao Chen, Chia-Chen Hsu, Chen-Shiung Chang,and Forest Shih-Sen Chien* “Surface-enhanced Raman scattering of graphene with photo-assisted-synthesized gold nanoparticles,” Optics Express, Vol. 21, Issue 5, p6547-6554 (2013/03). IF: 3.525, Rank: 7.2% (6/83).
17. Cheng-Wen Huang, Bing-Jie Lin, Hsing-Ying Lin, Chen-Han Huang, Fu-Yu Shih, Wei-Hua Wang, Chih-Yi Liu and Hsiang-Chen Chui*, “Surface-enhanced Raman scattering of suspended monolayer graphene,” Nanoscale Research Letters, 8:480 (2013/11). IF: 2.833, Rank: 18% (44/241).
18. Chen-Han Huang, Hsing-Ying Lin, Yonhua Tzeng, Chien-Hsiang Fan, Chih-Yi Liu, Chia-Yi Li, Cheng-Wen Huang, and Hsiang-Chen Chui*, “Optical characteristics of pore size on porous anodic aluminium oxide films with embedded silver nanoparticles,” Sensors & Actuators: A, Vol. 180, p49-54 (2012/06). IF: 2.201, Rank: 17% (10/56).
19. Chen-Han Huang, Hsing-Ying Lin, Yonhua Tzeng, Chien-Hsiang Fan, Chih-Yi Liu, Chia-Yi Li, Cheng-Wen Huang, and Hsiang-Chen Chui*, “Tunable Photoconductivity of Porous Anodic Aluminum Oxide with Silver Nanoparticles,” Electrochemical and Solid State Letters, Vol. 15, pJ14-J17 (2012/01). IF: 2.321, Rank: 25% (65/260).
20. Hsing-Ying Lin#, Chen-Han Huang#, Lai-Kwan Chau*, “Fiber Optic Particle Plasmon Resonance Sensor Based on Plasmonic Light Scattering Interrogation,” Annalen der Physik, Vol. 524(11), p705–712 (2012/11). IF: 3.443, Rank: 14% (11/79). (Invited Paper for Special Issue: Plasmonic Sensors.)
(co-first author)
21. Hsing-Ying Lin#, Chen-Han Huang#, Shannon Shy, Yu-Chung Chang*, Hsiang-Chen Chui*, and Chih-Han Chang, “Visibility Enhancement of Common Bile Duct for Laparoscopic Cholecystectomy by Vivid Fiber-optic Indication: A Porcine Experiment Trial,” Biomedical Optics Express, Vol. 3, p1964-1971 (2012/09). IF: 3.176, Rank: 8.7% (7/80).
22. Hsing-Ying Lin, Chen-Han Huang*, Gia-Ling Cheng, Nan-Kuang Chen, and Hsiang-Chen Chui, “Tapered optical fiber sensor based on localized surface plasmon resonance,” Optics Express, Vol. 20, p21693-21701 (2012/09). IF: 3.546, Rank: 6.2% (5/80), Cited: 49. (Selected in Virtual Journal for Biomedical Optics)
(corresponding author)
23. Hsing-Ying Lin, Chen-Han Huang*, Chia-Chi Huang, Yu-Chia Liu, and Lai-Kwan Chau*, “Multiple resonance fiber-optic sensor with time division multiplexing for multi-analyte detection,” Optics Letters, Vol. 37, p3969-3971 (2012/10). IF: 3.385, Rank: 7.5% (6/80).
(corresponding author)
24. Chia-Chi Huang, Chen-Han Huang, I-Ting Kuo, Lai-Kwan Chau*, Tzzy-Schiuan Yang*, “Synthesis of silica-coated gold nanorod as Raman tags by modulating cetyltrimethylammonium bromide concentration,” Colloid Surf. A-Physicochem. Eng. Asp., Vol. 409, p 161-166 (2012/09). IF: 2.76, Rank: 35% (50/139).
25. Cheng-Wen Huang, Hsing-Ying Lin, Chen-Han Huang, Kai-Hong Lo, Yu-Chung Chang,Chih-Yi Liu, Chen-Hao Wu, Yonhua Tzeng, and Hsiang-Chen Chui*, “Fluorescence Quenching due to Sliver Nanoparticles Covered by Graphene and Hydrogen-Terminated Graphene,” Appl. Phys. Lett., Vol 102, p053113 (2013/02). IF: 3.515, Rank: 14% (20/136).
26. Cheng-Wen Huang, Hsing-Ying Lin, Chen-Han Huang, Ren-Jye Shiue, Wei-Hua Wang, Chih-Yi Liu and Hsiang-Chen Chui*, “Layer-Dependent Morphologies of Silver on N-Layer Graphene,” Nanoscale Research Letters, 7:618 (2012/09). IF: 2.833, Rank: 18% (44/241).
27. S.-T. Chen, Y.-C. Chu, C.-Y. Liu, Chen-Han Huang, Y. Tzeng*, “Surface-enhanced Raman spectroscopy for characterization of nanodiamond seeded substrates and ultrananocrystalline diamond at the early-stage of plasma CVD growth process,” Diamond and Related Materials, Vol. 24, p161-166 (2012/04). IF: 2.561, Rank: 35% (97/275).
28. Cheng-Wen Huang, Bing-Jie Lin, Hsing-Ying Lin, Chen-Han Huang, Fu-Yu Shih, Wei-Hua Wang, Chih-Yi Liu and Hsiang-Chen Chui*, “Observation of Strain Effect on the Suspended Graphene by Polarized Raman Spectroscopy,” Nanoscale Research Letters, Vol. 7:533 (2012/09). IF: 2.78, Rank: 18% (44/241), Cited: 8.
29. Chen-Han Huang, Hsing-Ying Lin, Shihtse Chen, Chih-Yi Liu, Hsiang-Chen Chui, and Yonhua Tzeng*, “Electrochemically fabricated self-aligned 2-D silver/alumina arrays as reliable SERS sensors,” Optics Express, Vol. 19, p11441-11450 (2011/06). IF: 3.587, Rank: 7.5% (6/79).
30. K. R. Chen*, W. H. Chu, H. C. Fang, C. P. Liu, Chen-Han Huang, H. C. Chui, C. H. Chuang, Y. L. Lo, C. Y. Lin, H. H. Hwung, and Andy Y.-G. Fuh, “Beyond-limit light focusing in the intermediate zone,” Optics Letter, Vol. 36, p4497-4499 (2011/11). IF: 3.399, Rank: 8.8% (7/79)
31. Yi-Chi Lee, Chin-Chun Tsai, Yung-Yung Chang, Chen-Han Huang, and Hsiang-Chen Chui*, “Determining hyperfine transitions with electromagnetically induced transparency and optical pumping,” Chinese Physics B, Vol. 20, p073101 (2011/07). IF: 1.376.
32. Ben-Chao Lau, Chih-Yi Liu, Hsing-Ying Lin, Chen-Han Huang, Hsiang-Chen Chui, and Yonhua Tzeng*, “Electrochemical fabrication of anodic aluminum oxide films with encapsulated silver nanoparticles as plasmonic photoconductors,” Electrochemical and Solid-State Letters, Volume 14, E15-E17 (2011/02). IF: 2.321, Rank: 25% (65/260).
33. Hsing-Ying Lin, Chen-Han Huang, Chih-Han Chang, Yung-Chiang Lan, and Hsiang-Chen Chui*, “Direct near-field optical imaging of plasmonic resonances in metal nanoparticle pairs,” Optics Express, Vol. 18, p165-172 (2010). (Selected in Virtual Journal for Biomedical Optics)IF: 3.753, Rank: 6.4% (6/79).
34. Zong-Yan Zhuo, Chien-Sheng Liao, Chen-Han Huang, Jiun-Yann Yu, Yu-Yi Tzeng, Wen Lo, Chen-Yuan Dong, Hsiang-Chen Chui, Yu-Chan Huang, Hsi-Mei Lai, Shi-Wei Chu*, “Second harmonic generation imaging – A new method for unraveling molecular information of starch,” Journal of Structural Biology, Vol. 171, p88-94 (2010/07). IF: 3.50.
35. Chen-Han Huang, Hsing-Ying Lin, Ben-Chao Lau, Chih-Yi Liu, Hsiang-Chen Chui, Yonhua Tzeng*, “Plasmon-induced optical switching of electrical conductivity in porous anodic aluminum oxide films encapsulated with silver nanoparticle arrays,” Optics Express, Vol. 18, p27891-27899 (2010/11).
IF: 3.753, Rank: 6.4% (6/79).
36. Yan-Wei Tzeng, Yen-Yin Lin, Chen-Han Huang, Jian-Ming Liu, Hsiang-Chen Chui, Hsiang-Lin Liu, James M. Stone, Jonathan C. Knight, and Shi-Wei Chu*, “Broadband tunable optical parametric amplification from a single 50 MHz ultrafast fiber laser,” Optics Express, Vol. 17, Issue 9, p7304-7309 (2009/04).
IF: 3.278, Rank: 4.2% (3/71).
37. Jiun-Yann Yu, Chien-Sheng Liao, Zong-Yan Zhuo, Chen-Han Huang, Hsiang-Chen Chui, and Shi-Wei Chu*, “A diffraction-limited scanning system providing broad spectral range for laser scanning microscopy,” Review of Scientific Instruments, Vol. 80, p113704 (2009/11). IF: 1.521.
38. Chen-Han Huang, Hsing-Ying Lin, Hsiang-Chen Chui*, Yung-Chiang Lan, and Shi-Wei Chu, “The phase-response effect of size-dependent optical enhancement in a single nanoparticle,” Optics Express, Vol. 16, p9580-9586 (2008/06). IF: 3.88, Rank: 4.6% (5/78).
Book
39. Hsing-Ying Lin, Md. Nurunnabi, Wen-Hao Chen, Chen-Han Huang*, “Graphene in photoelectrochemical sensor and biosensor,” Chapter 16 of Book: Biomedical Applications of Graphene and 2D Nanomaterials; Publisher: ELSEVIER. Ltd. (2019)
40. Hsing-Ying Lin, Md. Nurunnabi, Wen-Hao Chen, Chen-Han Huang*, “Application of 2D nanomaterials in biomedical device,” Chapter 17 of Book: Biomedical Applications of Graphene and 2D Nanomaterials; Publisher: ELSEVIER. Ltd. (2019)
41. Hsing-Ying Lin, Ping-Ji Huang, Chen-Han Huang, Yen-Chieh Wang, Churng-Ren Chris Wang*, “Synthesis and optical properties of noble metal nanoparticles for biodetection,” Chapter 1 of Book: From Bioimaging to Biosensors: Noble Metal Nanoparticles in Biodetection; Publisher: Pan Stanford Publishing Pte. Ltd.; Editors: Lai-Kwan Chau, Huan-Tsung Chang; Publication Date: September 30, 2012 | ISBN-10: 9814267244 | ISBN-13: 978-9814267243 | Edition: 1.
Domestic publication
42. Hsing-Ying Lin, Chen-Han Huang, Lai-Kwan Chau,” Novel Optical Nanoprobes: SERS Tags for Biochemical Sensing and Applications,” CHEMISTRY (The Chinese Chemical Society, Taipei), Vol. 71, No. 3, pp. 243-2521 (2013).
43. Chen-Han Huang, Hsing-Ying Lin, Lai-Kwan Chau, “Novel Optical Nanoprobes: Raman-labeled Nanoaggregate-embedded Beads,” Taipei international invention show & technomart (2013/09), Taiwan nano exhibition (2013/10), Taiwan medical and biotech industry association (2013/12).
NCKU R&D News
44. Hsing-Ying Lin, Chen-Han Huang, Yun-Chiang Lan, Chih-Han Chang, and Hsiang-Chen Chui*, ”Plasmonic resonances of gold nanoparticle pairs,” Research Express@NCKU, Volume 24 Issue 1 (2013/05).
45. Chen-Han Huang, Hsing-Ying Lin, Hsiang-Chen Chui*, Yun-Chiang Lan, Chih-Han Chang, and Shi-Wei Chu, ”The phase-response effect of size-dependent optical enhancement in a single nanoparticle,” Research Express@NCKU, Volume 11 Issue 5 (2009/11).
EI and conference papers
1. Chen-Han Huang, Hsing-Ying Lin, Chien-Hsiang Fan, and Hsiang-Chen Chui*, “Near-infrared supercontinuum generation in conventional single mode fiber used for optical sensors,” 11th IEEE International Conference on Control & Automation (ICCA 2014), Taichung, Taiwan, (2014/06).
2. Chen-Han Huang*, Hsing-Ying Lin, Ling-Hsuan Liu, Shi-Ting Wang, I-Ting Kuo, Wen-Hsin Hsieh, Chiou-Ying Yang, and Lai-Kwan Chau*, “Bacteria detection using surface-enhanced Raman spectroscopic nanoprobes and dielectrophoretic microfluidic chip,” Biosensors 2014, 24th Anniversary World Congress on Biosensors, Melbourne, Australia, (2014/05).
3. Chen-Han Huang*, Hsing-Ying Lin, Ling-Hsuan Liu, Shi-Ting Wang, I-Ting Kuo, Wen-Hsin Hsieh, Chiou-Ying Yang, and Lai-Kwan Chau, “Bacteria detection using Raman-labeled nanoaggregate-embedded beads and dielectrophoretic chip,” EUROPT(R)ODE XII Conference on Optical Chemical Sensors & Biosensors, Athens, Greece, (2014/04).
4. Hsing-Ying Lin*, Chen-Han Huang, Lai-Kwan Chau, “Multiwindow fiber-optic plasmonic sensing based on light scattering,”EUROPT(R) ODE XII Conference on Optical Chemical Sensors & Biosensors, Athens, Greece,(2014/04).
5. Chen-Han Huang*, Hsing-Ying Lin, Wen-Hsin Hsieh, and Lai-Kwan Chau, “SERS Analysis for Pathogen Detection Using Raman-labeled Nanoaggregate-embedded Beads with A Dielectrophoretic Chip,” The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials (ASAM-4) , (2013/10).
6. Chen-Han Huang*, Hsing-Ying Lin, Wen-Hsin Hsieh, and Lai-Kwan Chau, “SERS Analysis for Pathogen Detection Using Raman-labeled Nanoaggregate-embedded Beads with A Dielectrophoretic Chip,” The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials (ASAM-4) , (2013/10).
7. Chen-Han Huang, Hsing-Ying Lin*, and Lai-Kwan Chau, “Tubular optical waveguide particle plasmon resonance biosensor for multiplex real-time and label-free detection,” Optical Sensors 2013, SPIE Optics + Optoelectronics, Prague, Czech Republic, (2013/04) (EI)
8. Chen-Han Huang*, Hsing-Ying Lin, and Lai-Kwan Chau, “Plasmonic Scattering Fiber Optic Sensor for Higher-Throughput Multianalyte Detection,” 3rd International Conference on Bio-Sensing Technology, Sitges, Spain, (2013/05).
9. Hsing-Ying Lin, Chen-Han Huang*, and Lai-Kwan Chau, “Multianalyte detection using fiber optic particle plasmon resonance sensor based on plasmonic light scattering interrogation,” Optical Sensors 2013, SPIE Optics + Optoelectronics, Prague, Czech Republic, (2013/04) (EI)
10. Hsing-Ying Lin, Chen-Han Huang*, Hsiang-Chen Chui, Meei-Ling Hung, “Silver nanoparticle distribution with the dependence of graphene layer number,” META’13, the 4th International Conference on Metamaterials, Photonic Crystals and Plasmonics, University of Sharjah, Sharjah, UAE, (2013/03) (submitted to Special issue of the journal Applied Physics A (Springer)) (EI)
11. Hsing-Ying Lin, Chen-Han Huang*, and Lai-Kwan Chau*, “Multiple Resonance Fiber-Optic Sensor with Multiplexing Technique for Simultaneous Multianalyte Detection,” 19th-Conference of Chemical Analysis Techniques (2103). (Invited Speaker)
12. Hsing-Ying Lin*, Chen-Han Huang, and Lai-Kwan Chau, “Dual Resonance Fiber-Optic Sensor with Frequency-Division
Multiplexing for Simultaneous Detection of Two Analytes,” 3rd International Conference on Bio-Sensing Technology, Sitges, (2013/05).
13. Hsing-Ying Lin*, Chen-Han Huang, Sin-Hong Lu, I-Ting Kuo, and Lai-Kwan Chau*, “Direct Detection of Orchid Viruses Using Gold Nanorod-Based Fiber Optic Particle Plasmon Resonance Immunosensor,” The 4th Asian Symposium on Advanced Materials - Chemistry, Physics & Biomedicine of Functional and Novel Materials (ASAM-4), (2013/10).
14. Hsing-Ying Lin, Chen-Han Huang, Hin-Hong Lu, I-Ting Kuo, and Lai-Kwan Chau*, “Detection of Orchid Viruses Using Nanorod-Based Fiber Optic Particle Plasmon Resonance Immunosensor,” 3rd International Conference on Bio-Sensing Technology, Sitges, Spain, (2013/05).
15. Meei-Ling Hung, Jeng-Wei Yang, Chen-Han Huang, Hsing-Ying Lin*, “Photoreduction mechanism of the sliver nanoparticles for active surface-enhanced Raman substrate by femtosecond laser,” The 7th Intelligent Systems Conference on Engineering Applications, (213/05) (EI).
16. Shi-Ting Wang, Hsing-Ying Lin, Chen-Han Huang, I-Ting Kuo, Lai-Kwan Chau*, “Development of Dielectrophoresis Chip Based on Gold Microelectrodes for Integration with Raman-Labeled Nanoaggregate-Embedded Beads in Pathogen Detection”, 19th-Conference of Chemical Analysis Techniques (2103).
17. Cheng-wen Huang, Bing-Jie Lin, Hsing-Ying Lin, Chen-Han Huang, Fu-Yu Shih, Wei-Hua Wang, Chih-Yi Liu, and Hsiang-Chen Chui*, “Probing Substrate Influence on Graphene by Raman Spectroscopy,” Annual Meeting of the Physics Society, Republic of China, Taiwan, (2103).
18. Chen-Han Huang, Hsing-Ying Lin, I-Ting Kuo, Wen-Hsin Hsieh, Ping-Ji Huang, Tzyy-Schiuan Yang, and Lai-Kwan Chau, “On-chip SERS analysis for single mimic pathogen detection using Raman-labeled nanoaggregate-embedded beads with a dielectrophoretic chip,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01). (EI)
19. Chen-Han Huang and Hsing-Ying Lin, “Fabrication of 2D metal nanoparticle array encapsulated by anodic aluminum oxide and its applications to surface-enhanced Raman scattering,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01) (EI)
20. Hsing-Ying Lin, Chen-Han Huang, Cheng-Wen Huang, Chia-Ling Cheng, Nan-Kuang Chen, Hsiang-Chen Chui*, “The localized surface plasmon resonance sensor based on tapered optical fiber modified with gold nanoparticles,” 2012 Asia Communications and Photonics Conference (ACP 2012), Guangzhou, China, (2012/11) (EI)
21. Hsing-Ying Lin, Chen-Han Huang, Yu-Chia Liu, Shin-Huei Chen, and Lai-Kwan Chau, “Tubular optical waveguide-based particle plasmon resonance biosensor for label-free and real-time detection,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01) (EI)
22. Hsing-Ying Lin, Chen-Han Huang, Yu-Chia Liu, Kuo-Wei Huang, and Lai-Kwan Chau, “Multiplex fiber-optic biosensor using multiple particle plasmon resonances,” 3rd Asia-Pacific Optical Sensors Conference 2012 (APOS 2012), Sydney, NSW, Australia, (2012/01). (EI)
23. Hsing-Ying Lin, Chen-Han Huang, Chia-Ling Cheng, Nan-Kuang Chen, and Hsiang-Chen Chui, “Tapered fiber-optic LSPR sensor with metal nanoparticle layers,” PIERS 2012, Moscow, Russia, (2012/08) (EI)
Patent
US patent
1. L.-K. Chau, C.-H. Huang, H.-Y. Lin, Y.-C. Liu, “Multiplex fiber optical biosensor and detection method by using the same,” US patent, No. US 9464986 B2, 2016/10/11
2. H.-C. Chui, S. S.-Y. Juang, H.-Y. Lin, C.-H. Huang, H.-H. Liao, “Ultraviolet laser sterilization system,” US patent, No. US9061083 B2, 2015/06/23
3. Y.-H. Tzeng, C.-Y. Liu, C.-H.-Huang, H.-Y. Lin, H.-C. Chui, K.-O. Lau, S.-T. Chen, C.-W. Huang, “Sensor chip for biomedical and micro-nano structured objects and materials and method providing the same,” US patent, No. US8902420, 2014/12/02
4. Yon-Hua Tzeng, Chih-Yi Liu, Kyaw-Oo Lau, Hsiang-Chen Chui, Chen-Han Huang, Hsing-Ying Lin, “Photo-sensitive composite film, method of fabricating the same, and photo-switched device comprising the same,” US patent, No. US008461511B2, 2013/06/11
5. Yen-Yin Lin, Yan-Wei Tzeng, Chen-Han Huang, Jian-Ming Liu, Shi-Wei Chu, “Wavelength Tunable Single-Pass Optical Parametric Amplifier,” US patent, No. US8369003B2, 2013/02/05
UK patent
6. CHAU, LAI KWAN, CHIANG, CHANG YUE, CHIANG, CHUNG SHENG, HSIEH, WEN HSIN, HUANG, CHEN HAN, “Optical waveguide type particle plasma resonance sensing system,” UK patent, No. GB2517955, 2016/06/08
Taiwan (ROC) patent
7. CHAU, LAI-KWAN, LIN, HSING-YING, HUANG, CHEN-HAN, LIU, LING-HSUAN, HSIEH, WEN-HSIN, “ MICROFLUIDIC BIOSENSING SYSTEM”, ROC Patent, No. I506265, 2015/11/01
8. CHAU, LAI KWAN, CHIANG, CHANG YUE, CHIANG, CHUNG SHENG, HSIEH, WEN HSIN, HUANG, CHEN HAN, “ OPTICAL WAVEGUIDE-PARTICLE PLASMON RESONANCE SENSING SYSTEM”, ROC Patent, No. I484155, 2015/05/11
9. CHAU, LAI KWAN, HUANG, CHEN HAN, LIN, HSING YING, LIU, YU CHIA, “ MULTIPLEX FIBER OPTICAL BIOSENSOR AND DETECTION METHOD BY USING THE SAME”, ROC Patent, No. I472746, 2015/02/11
10. TZENG, YON HUA, LIU, CHIH YI, KYAW, KYAW-OO, CHUI, HSIANG CHEN, HUANG, CHEN HAN, LIN, HSING YING, “ PHOTO-SWITCHED PATTERNED STRUCTURE AND METHOD OF FABRICATING THE SAME”, ROC Patent, No. I465611, 2014/12/21
11. TZENG, YON HUA, LIU, CHIH YI, HUANG, CHEN HAN, LIN, HSING YING, CHUI, HSIANG CHEN, LAU, KYAW-OO, CHEN, SHIH TSE, HUANG, CHENG WEN, “ SENSOR CHIP FOR BIOMEDICAL AND MICRO-NANO STRUCTURED OBJECTS AND MATERIALS AND METHOD PROVIDING THE SAME”, ROC Patent, No. I456195, 2014/10/11
12. LIN, YEN YIN, TZENG, YAN WEI, HUANG, CHEN HAN, LIU, JIAN MING, CHU, SHI WEI, “ WAVELENGTH TUNABLE SINGLE PASS OPTICAL PARAMETRIC AMPLIFIER”, ROC Patent, No. I408481, 2013/09/11
13. TZENG, YON HUA, LIU, CHIH YI, KYAW, KYAW-OO, CHUI, HSIANG CHEN, HUANG, CHEN HAN, LIN, HSING YING, “ PHOTO-SWITCHED ANODIZED ALUMINUM OXIDE FILM, METHOD OF FABRICATING THE SAME, AND PHOTO-SWITCHED DEVICE COMPRISING THE SAME”, ROC Patent, No. I406302, 2013/08/21
14. CHUI, HSIANG CHEN, JUANG, SEAN SUNG YEN, LIN, HSING YING, HUANG, CHEN HAN, LIAO, HUA HSIEN, “ ULTRAVIOLET LASER STERILIZATION SYSTEM’’, ROC Patent, No. 102129288, 2015/02/16
China patent
15. H.-C. Chui, S. S.-Y. Juang, H.-Y. Lin, C.-H. Huang, H.-H. Liao, “ Ultraviolet laser sterilization system,” China patent, No. CN 104368020 A, 2015/02/25
16. Y.-H. Tzeng, C.-Y. Liu, C.-H.-Huang, H.-Y. Lin, H.-C. Chui, K.-O. Lau, S.-T. Chen, C.-W. Huang, “ Sensor chip for biomedical and micro-nano structured objects and materials and method providing the same,” China patent, No. CN 102621122 A, CN 102621122 B, 2014/07/09
17. CHAU, LAI KWAN, CHIANG, CHANG YUE, CHIANG, CHUNG SHENG, HSIEH, WEN HSIN, HUANG, CHEN HAN, “ Optical waveguide type particle plasma resonance sensing system,” China patent, No. CN 104422669 A, 2015/03/18
Last Updated: 2023-11-19