welcome to Department of Biomedical Sciences & Engineering.

Faculties in Systems Biology and Bioinformatics

Associate Professor Li-Ching Wu

Posted on: 2022-06-04
Specialties:Bioinformatics, Biological databases, Deep learning, Medical informatics
Contact information:03-4227151(36106)
E-mail:nculcwu@gmail.com

Degree

National Central University, Ph.D. in Computer Science (1997/09~2004/07)
National Central University, M.S. in Computer Science (1995/09~1997/07)
National Central University, B.S. in Mathematics (1991/09~1995/07)


Experience
National Central University, Institute of Systems Biology and Bioinformatics, Associate Professor (2011/08~now)
National Central University, Institute of Systems Biology and Bioinformatics, Assistant Professor (2006/08~2011/07)
National Central University, Department of Computer Science and Information Engineering, Postdoctoral Researcher (2004/08~2006/07)

Journal Paper
1.L. C. Wu, J. T. Horng, H. S. Huang, F. M. Lin, H. D. Huang, and M. F. Tsai, “Primer design for multiplex PCR using a genetic algorithm”, Soft Computing, Vol. 11,no. 9 , pp. 855-863, 2007. (2010 IF. 1.512)
2. L. C. Wu, J. T. Horng, H. D. Huang, W. L. Chen, “Identifying Discriminative Amino Acids within the Hemagglutinin of Human Influenza A H5N1 Virus Using a Decision Tree”, IEEE Transactions on Information Technology in Biomedicine. Volume 12,  Issue 6, pp.689 - 695, 2008.(2010 IF. 1.707)
3. L. C. Wu, H. D. Huang, Y. C. Chang, Y. C. Lee and J. T. Horng,” Detecting LTR structures in human genomic sequences using profile hidden Markov model”, Expert Systems with Applications, Vol. 36, No. 1, pp.668-674, 2009. (2010 IF. 2.908)
4. Y.M. Sun, J. T. Horng,  J.H. Torng and L.C. Wu, “An expert system to identify transcription factor binding target genes by phylogenetic footprinting”, Expert Systems with Applications,. Vol. 36, No. 3, pp. 4923-4928, 2009. (2010 IF. 2.908)
5. J. T. Horng, L. C. Wu, B. J. Liu, J. L. Kuo, W.H. Kuo, and J. J. Zhang, "An expert system to classify microarray gene expression data using gene selection by decision tree", Expert Systems with Applications, Vol. 36, No. 5, pp. 9072-9081, 2009. (2010 IF. 2.908)
6. L. C. Wu, J. X. Lee, H. D. Huang, B. J. Liu, and J. T. Horng, "An expert system to predict protein thermostability using decision tree", Expert Systems with Applications, Vol. 36, No. 5, pp. 9007-9014, 2009. (2010 IF. 2.908)
7. T. H. Chang, H. D. Huang, L. C. Wu, C. T. Yeh, B.J. Liu, J. T. Horng, "Computational identification of riboswitches based on RNA conserved functional sequences and conformations", RNA, Vol. 15, Issue, 7, pp. 1426-1430, 2009. (2010 IF. 6.051)
8. L. C. Wu, J. T. Horng, Y. A. Chen, " A computation to integrate the analysis of genetic variations occurring within regulatory elements and their possible effects", Journal of Computational Biology, December 2009: 1731-1747. (2010 IF. 1.600)
9. L. C. Wu, J. L. Huang, J. T. Horng H. D. Huang, "An expert system to identify co-regulated gene groups from time-lagged gene clusters using cell cycle expression data ", Expert Systems with Applications, Vol. 37, No. 3, pp. 2202-2213, 2010. (2010 IF. 1.926)
10. L. C. Wu, H-H Chen, J. T. Horng, C. Lin, N. E. Huang, Y.C. Cheng, K. F. Cheng, " A Novel Preprocessing Method using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF Mass Spectrometry Data", PLOS ONE, Vol. 5, Issue 8, pp. E12493, 2010. (2010 IF. 4.411)
11. T. H. Chang, L. C. Wu, J. H. Lin, B. J. Liu, K. F. Cheng, J. T. Horng, "Prediction of small non-coding RNA in bacterial genomes using support vector machines", Expert Systems with Applications, Vol. 37, No. 8, pp. 5549-5557, 2010. (2010 IF. 2.908)
12. T. H. Chang, L. C. Wu, Y. T. Chen, H. D. Huang, B. J. Liu, K. F. Cheng, J. T. Horng, " Characterization and prediction of mRNA polyadenylation sites in human genes", Med Biol Eng Comput, 49:463-472, 2011. (2010 IF. 1.791)
13. C.H. Chen, H. C. Lee, Q. D. Ling, H. R. Chen, Y. A. Ko, T. S. Tsou, S. C. Wang, L. C. Wu, H. C. Lee, " An all-statistics, high-speed algorithm for the analysis of copy number variation in genomes", Nucleic Acids Research 2011, doi: 10.1093/nar/gkr137. (2010 IF. 7.836)
14. L. C. Wu, P. H. Hsieh, J. T. Horng, Y. J. Jou, C. D. Lin, K F Cheng, C W Lin and S Y Chen, "Improved Candidate Biomarker Detection Based on Mass Spectrometry Data Using the Hilbert-Huang Transform", Protein & Peptide Letters, Vol. 19, No. 1, Pp.120-129, 2012.
15. A. H. Tseng, F. H Chung, H. C. Lee, L. C. Wu, C. H. Chen and L. J. Su, "Microarray analysis and establishment of drug screening platform using 5-fluorouracil resistance HCT116 colon cancer cells", Genomic Medicine, biomarkers, and Health Science, Vol. 4, Issue 1, pp 21-27, 2012.
Last Updated: 2023-12-06