吳立青副教授
發布日期： 2022-06-04
專長：生物資訊、生物資料庫、深度學習、醫學資訊
連絡電話：03-4227151轉36106
E-mail：nculcwu@gmail.com
學歷
國立中央大學 資訊工程-博士(1997/09~2004/07)
國立中央大學 資訊工程-碩士(1995/09~1997/07)
國立中央大學 數學系-學士(1991/09~1995/07)
經歷
國立中央大學 系統生物與生物資訊研究所 副教授(2011/08~迄今)
國立中央大學 系統生物與生物資訊研究所 助理教授(2006/08~2011/07)
國立中央大學 資訊工程學系 博士後研究員(2004/08~2006/07)
論文著作
1.L. C. Wu, J. T. Horng, H. S. Huang, F. M. Lin, H. D. Huang, and M. F. Tsai, “Primer design for multiplex PCR using a genetic algorithm”, Soft Computing, Vol. 11,no. 9 , pp. 855-863, 2007. (2010 IF. 1.512)
2. L. C. Wu, J. T. Horng, H. D. Huang, W. L. Chen, “Identifying Discriminative Amino Acids within the Hemagglutinin of Human Influenza A H5N1 Virus Using a Decision Tree”, IEEE Transactions on Information Technology in Biomedicine. Volume 12, Issue 6, pp.689 - 695, 2008.(2010 IF. 1.707)
3. L. C. Wu, H. D. Huang, Y. C. Chang, Y. C. Lee and J. T. Horng,” Detecting LTR structures in human genomic sequences using profile hidden Markov model”, Expert Systems with Applications, Vol. 36, No. 1, pp.668-674, 2009. (2010 IF. 2.908)
4. Y.M. Sun, J. T. Horng, J.H. Torng and L.C. Wu, “An expert system to identify transcription factor binding target genes by phylogenetic footprinting”, Expert Systems with Applications,. Vol. 36, No. 3, pp. 4923-4928, 2009. (2010 IF. 2.908)
5. J. T. Horng, L. C. Wu, B. J. Liu, J. L. Kuo, W.H. Kuo, and J. J. Zhang, "An expert system to classify microarray gene expression data using gene selection by decision tree", Expert Systems with Applications, Vol. 36, No. 5, pp. 9072-9081, 2009. (2010 IF. 2.908)
6. L. C. Wu, J. X. Lee, H. D. Huang, B. J. Liu, and J. T. Horng, "An expert system to predict protein thermostability using decision tree", Expert Systems with Applications, Vol. 36, No. 5, pp. 9007-9014, 2009. (2010 IF. 2.908)
7. T. H. Chang, H. D. Huang, L. C. Wu, C. T. Yeh, B.J. Liu, J. T. Horng, "Computational identification of riboswitches based on RNA conserved functional sequences and conformations", RNA, Vol. 15, Issue, 7, pp. 1426-1430, 2009. (2010 IF. 6.051)
8. L. C. Wu, J. T. Horng, Y. A. Chen, " A computation to integrate the analysis of genetic variations occurring within regulatory elements and their possible effects", Journal of Computational Biology, December 2009: 1731-1747. (2010 IF. 1.600)
9. L. C. Wu, J. L. Huang, J. T. Horng H. D. Huang, "An expert system to identify co-regulated gene groups from time-lagged gene clusters using cell cycle expression data ", Expert Systems with Applications, Vol. 37, No. 3, pp. 2202-2213, 2010. (2010 IF. 1.926)
10. L. C. Wu, H-H Chen, J. T. Horng, C. Lin, N. E. Huang, Y.C. Cheng, K. F. Cheng, " A Novel Preprocessing Method using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF Mass Spectrometry Data", PLOS ONE, Vol. 5, Issue 8, pp. E12493, 2010. (2010 IF. 4.411)
11. T. H. Chang, L. C. Wu, J. H. Lin, B. J. Liu, K. F. Cheng, J. T. Horng, "Prediction of small non-coding RNA in bacterial genomes using support vector machines", Expert Systems with Applications, Vol. 37, No. 8, pp. 5549-5557, 2010. (2010 IF. 2.908)
12. T. H. Chang, L. C. Wu, Y. T. Chen, H. D. Huang, B. J. Liu, K. F. Cheng, J. T. Horng, " Characterization and prediction of mRNA polyadenylation sites in human genes", Med Biol Eng Comput, 49:463-472, 2011. (2010 IF. 1.791)
13. C.H. Chen, H. C. Lee, Q. D. Ling, H. R. Chen, Y. A. Ko, T. S. Tsou, S. C. Wang, L. C. Wu, H. C. Lee, " An all-statistics, high-speed algorithm for the analysis of copy number variation in genomes", Nucleic Acids Research 2011, doi: 10.1093/nar/gkr137. (2010 IF. 7.836)
14. L. C. Wu, P. H. Hsieh, J. T. Horng, Y. J. Jou, C. D. Lin, K F Cheng, C W Lin and S Y Chen, "Improved Candidate Biomarker Detection Based on Mass Spectrometry Data Using the Hilbert-Huang Transform", Protein & Peptide Letters, Vol. 19, No. 1, Pp.120-129, 2012.
15. A. H. Tseng, F. H Chung, H. C. Lee, L. C. Wu, C. H. Chen and L. J. Su, "Microarray analysis and establishment of drug screening platform using 5-fluorouracil resistance HCT116 colon cancer cells", Genomic Medicine, biomarkers, and Health Science, Vol. 4, Issue 1, pp 21-27, 2012.
連絡電話：03-4227151轉36106
E-mail：nculcwu@gmail.com
學歷
國立中央大學 資訊工程-博士(1997/09~2004/07)
國立中央大學 資訊工程-碩士(1995/09~1997/07)
國立中央大學 數學系-學士(1991/09~1995/07)
經歷
國立中央大學 系統生物與生物資訊研究所 副教授(2011/08~迄今)
國立中央大學 系統生物與生物資訊研究所 助理教授(2006/08~2011/07)
國立中央大學 資訊工程學系 博士後研究員(2004/08~2006/07)
論文著作
1.L. C. Wu, J. T. Horng, H. S. Huang, F. M. Lin, H. D. Huang, and M. F. Tsai, “Primer design for multiplex PCR using a genetic algorithm”, Soft Computing, Vol. 11,no. 9 , pp. 855-863, 2007. (2010 IF. 1.512)
2. L. C. Wu, J. T. Horng, H. D. Huang, W. L. Chen, “Identifying Discriminative Amino Acids within the Hemagglutinin of Human Influenza A H5N1 Virus Using a Decision Tree”, IEEE Transactions on Information Technology in Biomedicine. Volume 12, Issue 6, pp.689 - 695, 2008.(2010 IF. 1.707)
3. L. C. Wu, H. D. Huang, Y. C. Chang, Y. C. Lee and J. T. Horng,” Detecting LTR structures in human genomic sequences using profile hidden Markov model”, Expert Systems with Applications, Vol. 36, No. 1, pp.668-674, 2009. (2010 IF. 2.908)
4. Y.M. Sun, J. T. Horng, J.H. Torng and L.C. Wu, “An expert system to identify transcription factor binding target genes by phylogenetic footprinting”, Expert Systems with Applications,. Vol. 36, No. 3, pp. 4923-4928, 2009. (2010 IF. 2.908)
5. J. T. Horng, L. C. Wu, B. J. Liu, J. L. Kuo, W.H. Kuo, and J. J. Zhang, "An expert system to classify microarray gene expression data using gene selection by decision tree", Expert Systems with Applications, Vol. 36, No. 5, pp. 9072-9081, 2009. (2010 IF. 2.908)
6. L. C. Wu, J. X. Lee, H. D. Huang, B. J. Liu, and J. T. Horng, "An expert system to predict protein thermostability using decision tree", Expert Systems with Applications, Vol. 36, No. 5, pp. 9007-9014, 2009. (2010 IF. 2.908)
7. T. H. Chang, H. D. Huang, L. C. Wu, C. T. Yeh, B.J. Liu, J. T. Horng, "Computational identification of riboswitches based on RNA conserved functional sequences and conformations", RNA, Vol. 15, Issue, 7, pp. 1426-1430, 2009. (2010 IF. 6.051)
8. L. C. Wu, J. T. Horng, Y. A. Chen, " A computation to integrate the analysis of genetic variations occurring within regulatory elements and their possible effects", Journal of Computational Biology, December 2009: 1731-1747. (2010 IF. 1.600)
9. L. C. Wu, J. L. Huang, J. T. Horng H. D. Huang, "An expert system to identify co-regulated gene groups from time-lagged gene clusters using cell cycle expression data ", Expert Systems with Applications, Vol. 37, No. 3, pp. 2202-2213, 2010. (2010 IF. 1.926)
10. L. C. Wu, H-H Chen, J. T. Horng, C. Lin, N. E. Huang, Y.C. Cheng, K. F. Cheng, " A Novel Preprocessing Method using Hilbert Huang Transform for MALDI-TOF and SELDI-TOF Mass Spectrometry Data", PLOS ONE, Vol. 5, Issue 8, pp. E12493, 2010. (2010 IF. 4.411)
11. T. H. Chang, L. C. Wu, J. H. Lin, B. J. Liu, K. F. Cheng, J. T. Horng, "Prediction of small non-coding RNA in bacterial genomes using support vector machines", Expert Systems with Applications, Vol. 37, No. 8, pp. 5549-5557, 2010. (2010 IF. 2.908)
12. T. H. Chang, L. C. Wu, Y. T. Chen, H. D. Huang, B. J. Liu, K. F. Cheng, J. T. Horng, " Characterization and prediction of mRNA polyadenylation sites in human genes", Med Biol Eng Comput, 49:463-472, 2011. (2010 IF. 1.791)
13. C.H. Chen, H. C. Lee, Q. D. Ling, H. R. Chen, Y. A. Ko, T. S. Tsou, S. C. Wang, L. C. Wu, H. C. Lee, " An all-statistics, high-speed algorithm for the analysis of copy number variation in genomes", Nucleic Acids Research 2011, doi: 10.1093/nar/gkr137. (2010 IF. 7.836)
14. L. C. Wu, P. H. Hsieh, J. T. Horng, Y. J. Jou, C. D. Lin, K F Cheng, C W Lin and S Y Chen, "Improved Candidate Biomarker Detection Based on Mass Spectrometry Data Using the Hilbert-Huang Transform", Protein & Peptide Letters, Vol. 19, No. 1, Pp.120-129, 2012.
15. A. H. Tseng, F. H Chung, H. C. Lee, L. C. Wu, C. H. Chen and L. J. Su, "Microarray analysis and establishment of drug screening platform using 5-fluorouracil resistance HCT116 colon cancer cells", Genomic Medicine, biomarkers, and Health Science, Vol. 4, Issue 1, pp 21-27, 2012.
更新日期: 2023-12-06