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Faculties inTranslational and Interdisciplinary Medicine

Associate Professor Chen Lin

Posted on: 2021-06-08

National Central University, Taiwan
Ph.D. in Institute of Systems Biology and Bioinformatics
Current Position
Associate Professor, Department of Biomedical Sciences and Engineering, National Central University
Previous appointments and professional experiences
Assistant Professor, Department of Biomedical Sciences and Engineering, National Central University

Assistant Research Fellow
Center for Adaptive Data Analysis, National Central University

Taiwanese Team of Qualcomm Tricorder XPRIZE Competition (Co-PI in Vital Sign Group)

Post-Doctoral Fellow
Department of Behavioral Science and Psychiatry, Stanford University

1. Pham V-T, Lin C*, Tran T-T, Su M-Y M., Lin Y-K, Nien C-T, Tseng W-Y I., Lin J-L, Lo M-T, Lin L-Y, Predicting ventricular tachyarrhythmia in patients with systolic heart failure based on texture features of the gray zone from contrast-enhanced magnetic resonance imaging. Journal of Cardiology, 2020, S0914-5087(20)30222-7 (*corresponding author)
2. Lin C, Lin P-F, Wang C-H, Juan C-H, Tran T-T, Nien C-T, Lin YJ, Wang C.Y., Yeh CH, and Lo MT, Probing age-related changes in cardio-respiratory dynamics by multimodal coupling assessment. Chaos, 2020, 30:033118
3. Lin Y-K, Kao C-C, Tseng C-H, Hsu C-E, Lin Y-J, Chen Y-C, Lin C*, and C-Y Huang, Noninvasive Hemodynamic Profiles during Hemodialysis in Patients with and without Heart Failure. Cardiorenal Medicine, 2020,10(4):243-256 (*corresponding author)
4. Lin C, Wong B-Y, Lo M-T, Chiu Y-C, and Lin Y-H, Development of an addiction index and delineation 15-year trends of illicit drugs from a nationwide drug enhancement database. Journal of Psychiatric Research, 2020, 120(1):131-136
5. Kao C-C, Tseng C-H, Lo M-T, Lin Y-K, Hsu C-Y, Wu Y-L, Chen H-H, Lin F-Y, C Lin*, and C-Y Huang Alteration autonomic control of cardiac function during hemodialysis predict cardiovascular outcomes in end stage renal disease patients Scientific Reports, 2019, 9:18783 (*corresponding author)
6. Tseng C-H, Lin C*, Chang H-C, Liu C-C, Serafico BMF, Wu L-C, Lin C-T, Hsu T, Huang C-Y, and M-T Lo Cloud-Based Artificial Intelligence System for Large-Scale Arrhythmia Screening Computer, 2019, 52(11):40-51 (*corresponding author)
7. Lin C*, Yeh C-H, Wang C-Y, Shi W, Serafico BMF, Wang C-H, Juan C-H, Young H-W Vincent, Lin Y-J, Yeh H-M, and Lo M-T, Robust Fetal Heart Beat Detection via R-peak Intervals Distribution. IEEE Transactions on Biomedical Engineering, 2019, 66(12):3310-3319 (* corresponding author)
8. Tsai C-H, Ma H-P, Lin Y-T, Hung C-S, Hsieh M-C, Chang T-Y, Kuo P-H, Lin C*, Lo M-T, Hsu H-H, Peng C-K, and Lin Y-H, Heart Rhythm Complexity Impairment in Patients with Pulmonary Hypertension, Scientific Reports, 2019, 9:10710 (*corresponding author)
9. Lin C, Lo M-T, and Guilleminault C, Exploring the abnormal modulation of the autonomic systems during nasal flow limitation in upper airway resistance syndrome by Hilbert–Huang transform. Frontiers in Medicine, 2017, 4(161)
10. Lin C, Chang Y-C, Cheng Y-C, Lai P-J, Yeh C-H, Hsieh W-H, Hu K, Wu J-T, Lee H-H, M-T Lo, and Y-L Ho, Probing the fractal pattern of heartbeats in Drosophila pupae by visible optical recording system Scientific Reports, 2016, 6: 31950
11. Tsai C-H, Huang J-W, Lin C., Ma H-P, Lo M-T, Liiu L-YD, Lin L-Y, Lin C-T, Hung C-S, Peng C-K, and Lin Y-H Heart Rhythm Complexity Predicts Long‐Term Cardiovascular Outcomes in Peritoneal Dialysis Patients: A Prospective Cohort Study. Journal of the American Heart Association, 2020, 9(2):e013036  (IF=4.660, 34/136; CARDIAC & CARDIOVASCULAR SYSTEMS
12. Tran T-T, Pham V-T, Lin C, Yang HW, Wang YH, Shyu KK, Tseng WYI, Su MY, Lin LY, Lo M-T, “Empirical Mode Decomposition and Monogenic Signal-Based Approach for Quantification of Myocardial Infarction From MR Images”IEEE Journal of Biomedical and Health Informatics 2018,23(2):731-743
13. Yeh C-H, Juan C-H, Yeh H-M, Wang C.Y. Young H-WV, Lin J-L, Lin C, Lin L-Y, and Lo M-T The critical role of respiratory sinus arrhythmia on temporal cardiac dynamics. Journal of Applied Physiology, 2019, 127(6):1733-1741
14. Tran TT, Fang TY, Pham VT, Lin C, Wang PC, and Lo M-T, “Development of an Automatic Diagnostic Algorithm for Pediatric Otitis Media”, Otology & Neurotology, 2018 Sep;39(8):1060-1065.(IF=2.063, Rank:15/42;OTORHINOLARYNGOLOGY)
15. Yang HW, Jeng SK, Young HWV, Lin C, Wang YH, Hu K, and Lo M-T, “A Minimum Arclength Method for Removing Spikes in Empirical Mode Decomposition”, IEEE ACCESS, 2019, 7:13284 (IF=4.098, Rank:23/155; COMPUTER SCIENCE, INFORMATION SYSTEMS)
16. Gao L, Li P, Hu C, To T, Patxot M, Falvey B, Wong PM, Scheer FAJL, Lin C, Lo MT,and Hu K “Nocturnal Heart Rate Variability Moderates the Association Between Sleep-Wake Regularity and Mood in Young Adults.” Sleep, 2019, 42(5) (IF=4.571, Rank: 32/199, CLINICAL NEUROLOGY)
17. Y.-H. Lin, M.-T. Lo, X.-M. Wu, C.-S. Hung, Y.-L. Ho, K.-D. Wu, C. Lin*, V.-C. Wu, M. Stowasser, C.-K. Peng and the TAIPAI Study Group “Adrenalectomy reverses the impaired heart rhythm complexity in patients with primary aldosteronism” Scientific Reports, 2015 5:11249 (*corresponding author)
18. M.-T Lo, Y.-C. Chang, C. Lin, Vincent H.-W. Young, Y.-H. Lin, Y.-L. Ho, C.-K. Peng, K. Hu “Outlier-resilient complexity analysis of heartbeat dynamics” Scientific Reports, 2015, 5:8836
19. P.-F. Lin, J. Tsao, M.-T. Lo, C. Lin, Y.-C. Chang “Symbolic Entropy of the Amplitude rather than the Instantaneous Frequency of EEG Varies in Dementia”, Entropy, 2015 Jan; 17(2): 560-579

Ministry of Science and Technology
·  2019-2021 A Multi-Signal Based Automated Monitoring System for Pediatric Sleep Disorders
·  2017  Industry-Academy cooperation project of Hsinchu Science Park Bureau-“An integrated platform for early screening of sleep breathing disorders.”
·  2014-2017   Realization of a wearable device for biomarker detection and cloud computation based feedback (Subproject 3 : Exploiting biomarkers of physiological signals recorded from wearable devices by using adaptive data analysis)
Joint Research Grants
·    2017 Joint Project of National Central University and Landseed Hospital-Exploring the associations among in-patient longitudinal changes of vital signs, laboratory data of acute exacerbations of chronic obstructive pulmonary disease and their prognosis by machine learning.”

  • 1. Method and system for extracting ventricular fibrillation signals in electrocardiogram  using  spline interpolation with uniform phase ensembles US 9451898 B2 Sep, 2016
  • 2. System and method for quantitative analysis of respiratory sinus arrhythmia US 9380948 B1 Jul, 2016
  • 3. Method and system for extracting ventricular fibrillation signals in electrocardiogram, US 9259167 B2 Feb, 2016
Last Updated: 2022-06-09