歡迎光臨 國立中央大學生醫科學與工程學系

 

1.CY Hsiao, LJ Su, KH Yu, TM Chan. Clinical significance of cytoplasmic discrete dots (AC-18) patterns in HEp-2 cell indirect Immunofluorescence: insights from a Taiwanese multicenter study. Clinica Chimica Acta. 2025; 578: 120521. 

 

2.Chiu SH, Hsia JY, Yang TY, Huang YX, Wang GZ Liu YC, Wang YW, He F, Chen JMM, Zhao GJ, Lyu PC, Su LJ, Yu CTR, Wei TYW. Mechanistic Insights into CLNS1A-Mediated Chemoresistance and Tumor Progression in Lung Cancer. Cancer Lett. 2025; 626:217783

 

3.Chung MC, Su LJ, Wu LC. Revealing the antimicrobial potential of traditional Chinese medicine through text mining and molecular computation. Briefings in Bioinformatics. 2025; 26(1): bbaf077. 

 

4.Tsai MH, Chen CH, Chen CL, Lee MH, Wu LC, Hsu YC, Hsiao CY, Lee CT, Pi KL, Su LJ. Areca catechu L. inhibits colorectal cancer tumor growth by modulating cell apoptosis and autophagy. Curr Issues Mol Biol. 2025;47(2):128.

 

5.Hsiao CY, Tseng SC, Hsu CY, Chiu LC, Su LJ, Chan TM. Clinical features of anti-SAE1 antibody-positive myositis and interstitial lung disease: a multicenter, retrospective study in Taiwan. Front Immunol. 2024;15: 1482000.

 

6.Chung MC, Su LJ, Chen CL, Wu LC. AI-assisted literature exploration of innovative Chinese medicine formulas. Front Pharmacol. 2024; 15: 1347882.

 

7.Wang BY, Chang YY, Shiu LY, Lee YJ, Lin YW, Hsu YS, Tsai HT, Hsu SP, Su LJ, Tsai MH, Xiao JH, Lin JA, Chen CH. An integrated analysis of dysregulated SCD1 in human cancers and functional verification of miR-181a-5p/SCD1 axis in esophageal squamous cell carcinoma. Comput Struct Biotechnol J. 2023; 21: 4030-4043.

 

8.Huang TL, Chang CR, Chien CY, Huang GK, Chen YF, Su LJ, Tsai HT, Lin YS, Fang FM, Chen CH. DRP1 contributes to head and neck cancer progression and induces glycolysis through modulated FOXM1/MMP12 axis. Mol Oncol. 2022; 16(13): 2585-2606. 

 

9.Luo SD, Tsai HT, Chiu TJ, Li SH, Hsu YL, Su LJ, Tsai MH, Lee CY, Hsiao CC, Chen CH. Leptin Silencing Attenuates Lipid Accumulation through Sterol Regulatory Element-Binding Protein 1 Inhibition in Nasopharyngeal Carcinoma. Int J Mol Sci. 2022; 23(10): 5700. 

 

10.Liu CC, Lee HC, Peng YS, Tseng AH, Wu JL, Tsai WY, Wong CS, Su LJ. Transcriptome Analysis Reveals Novel Genes Associated with Cartilage Degeneration in Posttraumatic Osteoarthritis Progression. Cartilage. 2021; 13(2_suppl): 1249S-1262S.

 

11.Keshari S, Sipayung AD, Hsieh CC, Su LJ, Chiang YR, Chang HC, Yang WC, Chuang TH, Chen CL, Huang CM. IL-6/p-BTK/p-ERK signaling mediates calcium phosphate-induced pruritus. FASEB J. 2019; 33(11): 12036-12046. 

 

12.Li TL, Wu MW, Lin WC, Lai CH, Chang YH, Su LJ, Chen WY. Designed phosphate-methylated oligonucleotides as PCR primers for SNP discrimination. Anal Bioanal Chem. 2019l; 411(17):3871-3880. 

 

13.Chen CH, Su LJ, Tsai HT, Hwang CF. ELF-1 expression in nasopharyngeal carcinoma facilitates proliferation and metastasis of cancer cells via modulation of CCL2/CCR2 signaling. Cancer Manag Res. 2019; 11:5243-5254. 

 

14.Wu YC, Wei NC, Hung JJ, Yeh YC, Su LJ, Hsu WH, Chou TY. Generating a robust prediction model for stage I lung adenocarcinoma recurrence after surgical resection. Oncotarget. 2017; 8(45):79712-79721. 

 

15.Chen CH, Tsai HT, Chuang HC, Shiu LY, Su LJ, Chiu TJ, Luo SD, Fang FM, Huang CC, Chien CY. Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A. Sci Rep. 2017; 7(1):1358. 

 

16.Su LJ, Ye JJ, Shiu LY. Carnosic Acid Inhibits Human Squamous Cell Carcinoma Cell Line SCC-25 Proliferation. Int J of Head and Neck Sci. 2017; 1(2): 141-145.

 

17.Shiu LY, Lai CH, Yang CH, Tseng AH, Lee HC, Su LJ. Identification of Genomic Alterations in Head and Neck Squamous Cell Carcinoma and Esophageal Squamous Cell Carcinoma. Int J of Head and Neck Sci. 2017; 1(1): 47-84.

 

18.Tseng A, Yang CH, Chen CH, Chen CH, Hsu SL, Lee MH, Lee HC, Su LJ. An in vivo molecular response analysis of colorectal cancer treated with Astragalus membranaceus extract. Oncol Rep. 2016; 35(2):659-68. 

19.Liu CC, Su LJ, Tsai WY, Sun HL, Lee HC, Wong CS. Hylan G-F 20 attenuates posttraumatic osteoarthritis progression: Association with upregulated expression of the circardian gene NPAS2. Life Sci. 2015; 141: 20-4. 

 

20.Chen CH, Chang AY, Li SH, Tsai HT, Shiu LY, Su LJ, Wang WL, Chiu TJ, Luo SD, Huang TL, Chien CY. Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer. Mol Cancer. 2015; 14: 83. 

 

21.Chen CH, Hsu CL, Huang SH, Chen SY, Hung YL, Chen HR, Wu YC, Su LJ, Lee HC. Method designed to respect molecular heterogeneity can profoundly correct present data interpretations for genome-wide expression analysis. PLoS One. 2015; 10(3): e0121154. 

 

22.Huang HL, Wu YC, Su LJ, Huang YJ, Charoenkwan P, Chen WL, Lee HC, Chu WC, Ho SY. Discovery of prognostic biomarkers for predicting lung cancer metastasis using microarray and survival data. BMC Bioinformatics. 2015; 16: 54. 

 

23.Wei TY, Hsia JY, Chiu SC, Su LJ, Juan CC, Lee YC, Chen JM, Chou HY, Huang JY, Huang HM, Yu CT. Methylosome protein 50 promotes androgen- and estrogen-independent tumorigenesis. Cell Signal. 2014; 26(12): 2940-50. 

 

24.Chiang KC, Yeh CN, Lin KJ, Su LJ, Yen TC, Pang JH, Kittaka A, Sun CC, Chen MF, Jan YY, Chen TC, Juang HH, Yeh TS. Chemopreventive and chemotherapeutic effect of dietary supplementation of vitamin D on cholangiocarcinoma in a Chemical-Induced animal model. Oncotarget. 2014; 5(11): 3849-61. 

 

25.Chien CY, Tsai HT, Su LJ, Chuang HC, Shiu LY, Huang CC, Fang FM, Yu CC, Su HT, Chen CH. Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior. Oncotarget. 2014; 5(8): 2243-62. 

 

26.Hwang CF, Shiu LY, Su LJ, Yu-Fang Yin, Wang WS, Huang SC, Chiu TJ, Huang CC, Zhen YY, Tsai HT, Fang FM, Huang TL, Chen CH. Oncogenic fibulin-5 promotes nasopharyngeal carcinoma cell metastasis through the FLJ10540/AKT pathway and correlates with poor prognosis. PLoS One. 2013; 8(12): e84218. 

 

27.Chen CH, Chuang HC, Huang CC, Fang FM, Huang HY, Tsai HT, Su LJ, Shiu LY, Leu S, Chien CY. Overexpression of Rap-1A indicates a poor prognosis for oral cavity squamous cell carcinoma and promotes tumor cell invasion via Aurora-A modulation. Am J Pathol. 2013;182 (2): 516-28. 

 

28.Su LJ, Chang CC, Yang CH, Hsieh SJ, Wu YC, Lai JM, Tseng TL, Huang CY, Hsu SL. Graptopetalum paraguayense ameliorates chemical-induced rat hepatic fibrosis in vivo and inactivates stellate cells and Kupffer cells in vitro. PLoS One. 2013; 8(1): e53988. 

 

29.Wei TY, Juan CC, Hisa JY, Su LJ, Lee YC, Chou HY, Chen JM, Wu YC, Chiu SC, Hsu CP, Liu KL, Yu CT. Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin-dependent kinases and the phosphoinositide 3-kinase/AKT signaling cascade. Cancer Sci. 2012; 103(9): 1640-50. 

 

30.Chen CH, Shiu LY, Su LJ, Huang CY, Huang SC, Huang CC, Yin YF, Wang WS, Tsai HT, Fang FM, Chuang WC, Kang HC, Hwang CF. FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway. J Transl Med. 2012; 10: 93. 

 

31.Chiang KC, Yeh CN, Chen SC, Shen SC, Hsu JT, Yeh TS, Pang JH, Su LJ, Takano M, Kittaka A, Juang HH, Chen TC. MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D(3) in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells. Evid Based Complement Alternat Med. 2012; 2012: 310872. 

 Su LJ, Yang CH, Huang SF, Yuo YL, Hsieh HC, Tseng TL, Chen CH, Hsu SL, Huang CY. Evaluation of the Chinese Medicinal Herb, Graptopetalum paraguayense, as a Therapeutic Treatment for Liver Damage in Rat Models. Evid Based Complement Alternat Med. 2012; 2012: 256561. 

doi: 10.1155/2012/256561. PMID: 22811744

 

32.Yu CT, Hsia JY, Hseih YC, Su LJ, Lee TC, Ku CF, Chen KS, Chen JM, Wei TY, Lee YC, Huang CY, Wu YC, Yang CY, Hsu SL. The novel protein suppressed in lung cancer down-regulated in lung cancer tissues retards cell proliferation and inhibits the oncokinase Aurora-A. J Thorac Oncol. 2011; 6(6): 988-97. 

 

33.Hwang CF, Chien CY, Huang SC, Yin YF, Huang CC, Fang FM, Tsai HT, Su LJ, Chen CH. Fibulin-3 is associated with tumour progression and a poor prognosis in nasopharyngeal carcinomas and inhibits cell migration and invasion via suppressed AKT activity. J Pathol. 2010; 222(4): 367-79. 

 

34.Wu YC, Su LJ, Wang HW, Jeff Lin CF, Hsu WH, Chou TY, Huang CY, Lu CL, Hsueh CT. Co-overexpression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 adversely affects the postoperative survival in non-small cell lung cancer. J Thorac Oncol. 2010; 5(8): 1167-74. 

 

35.Chen CH, Lai JM, Chou TY, Chen CY, Su LJ, Lee YC, Cheng TS, Hong YR, Chou CK, Whang-Peng J, Wu YC, Huang CY. VEGFA upregulates FLJ10540 and modulates migration and invasion of lung cancer via PI3K/AKT pathway. PLoS One. 2009; 4(4): e5052. 

 

36.Wong FH, Huang CY, Su LJ, Wu YC, Lin YS, Hsia JY, Tsai HT, Lee SA, Lin CH, Tzeng CH, Chen PM, Chen YJ, Liang SC, Lai JM, Yen CC. Combination of microarray profiling and protein-protein interaction databases delineates the minimal discriminators as a metastasis network for esophageal squamous cell carcinoma. Int J Oncol. 2009; 34(1): 117-28.

 

37.Su LJ, Chang CW, Wu YC, Chen KC, Lin CJ, Liang SC, Lin CH, Whang-Peng J, Hsu SL, Chen CH, Huang CY. Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. BMC Genomics. 2007; 8: 140. 

 

38.Hsu CN, Lai JM, Liu CH, Tseng HH, Lin CY, Lin KT, Yeh HH, Sung TY, Hsu WL, Su LJ, Lee SA, Chen CH, Lee GC, Lee DT, Shiue YL, Yeh CW, Chang CH, Kao CY, Huang CY. Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (Encyclopedia of Hepatocellular Carcinoma genes Online). BMC Bioinformatics. 2007; 8: 66. 

 

39.Su LJ, Hsu SL, Yang JS, Tseng HH, Huang SF, Huang CY. Global gene expression profiling of dimethylnitrosamine-induced liver fibrosis: from pathological and biochemical data to microarray analysis. Gene Expr. 2006; 13(2): 107-32. 

 

40.Lin YS, Su LJ, Yu CT, Wong FH, Yeh HH, Chen SL, Wu JC, Lin WJ, Shiue YL, Liu HS, Hsu SL, Lai JM, Huang CY. Gene expression profiles of the aurora family kinases. Gene Expr. 2006; 13(1): 15-26. 

 

41.Tien AC, Lin MH, Su LJ, Hong YR, Cheng TS, Lee YC, Lin WJ, Still IH, Huang CY. Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model. Mol Cell Proteomics. 2004; 3(1): 93-104. 

 

42.Chao CC, Su LJ, Sun NK, Ju YT, Lih JC, Lin-Chao S. Involvement of Gas7 in nerve growth factor-independent and dependent cell processes in PC12 cells. J Neurosci Res. 2003; 74(2): 248-54.